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| Author(s): |
Kélem de Nardi Chagas
Total Authors: 1
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| Document type: | Doctoral Thesis |
| Press: | São Paulo. |
| Institution: | Universidade de São Paulo (USP). Faculdade de Medicina (FM/SBD) |
| Defense date: | 2005-08-17 |
| Examining board members: |
Anete Sevciovic Grumach;
Raymundo Soares de Azevedo Neto;
Gil Benard;
Eitan Naaman Berezin;
Antonio Zuliani
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| Advisor: | Anete Sevciovic Grumach |
| Abstract | |
It was evaluated the mbl2 gene expression in 79 children and their HIV positive mothers with the aim to evaluate its influence on mother-to-child HIV. The patients were divided in two groups: HIV positive children and their mothers (n=18) and HIV negative children and their mothers (n=61) were evaluated by CH50 and AP50 (hemolytic assays); levels and functional MBL and terminal complement cascade (ELISA) and mbl2 gene (PCR). The results didn't show significant difference amons serum levels, functional activities and MBL gene between the groups, excluding the influence in the mother-to child HIV transmission. (AU) | |