Full text
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| Author(s): |
Fernando Pando de Matos
Total Authors: 1
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| Document type: | Master's Dissertation |
| Press: | Ribeirão Preto. |
| Institution: | Universidade de São Paulo (USP). Faculdade de Odontologia de Ribeirão Preto (PCARP/BC) |
| Defense date: | 2012-08-31 |
| Examining board members: |
Cassio Edvard Sverzut;
Idelmo Rangel Garcia Junior;
Joao Gualberto de Cerqueira Luz
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| Advisor: | Cassio Edvard Sverzut |
| Abstract | |
The aim of this study was to evaluate histologic and histometrically the bone repair in mandibular body osteotomy and bone-screw interface after using a biodegradable 2.0-mm internal fixation system. Six dogs were subjected to an unilateral osteotomy in mandibular body (experimental side), which was stabilized by applying two 4-hole plates manufactured with poly-L-DL-lactic acid (70:30). In the opposite side (control side), a superficial demarcation on the buccal cortical was performed and half of the IF system (two 2-hole plates) was applied. After 2 and 18 weeks, the dogs were euthanized and the osteotomy site and the bone-screw interface were removed for microscopic analysis. Each screw was sectioned along its long axis and the osteotomy sites were divided equally into three parts: the upper part was labelled the Tension Third (TT), the lower part Compression Third (CT), and the part between the TT and CT Intermediary Third (IT). Histologic analysis showed areas of direct contact between the screw surface and the parent lamellar bone at 2 weeks. At 18 weeks, three microscopically distinct layers at the bone-screw interface were noted. No statistically significant difference was observed in the bone-to-screw contact between the control and experimental sides for each time point. At the osteotomy sites, union between the bone fragments was observed at 18 weeks characterized by interconnected parallel-fibered bone trabeculae and some newly formed osteonal systems. Statistically significant difference of newly formed bone among TT, IT and CT (p=0.019) was observed. In conclusion, the biodegradable IF system used in this study was able to allow the bone repair at the osteotomy site due to the biomechanical environment created and the characteristics of the tissue adjacent to the biodegradable screws were highly influenced by the properties of the poly-LDL- lactic acid (70:30). (AU) | |
| FAPESP's process: | 10/02277-1 - Histologic and histometric analysis of the osteotomy and bone-screw interface in the mandibular body after using an absorbable 2.0 mm miniplates system: an experimental study in dogs |
| Grantee: | Fernando Pando de Matos |
| Support Opportunities: | Scholarships in Brazil - Master |