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ANALGESIC PEPTIDES DERIVED FROM THE VENOM OF CROTALUS DURISSUS TERRIFICUSS SNAKES

Document type:Patente
Inventor(s): Yara Cury; Gisele Picolo; Katsuhiro Konno; Renata Giorgi; Patrícia Brigatte; Vanessa Pacciari Gutierrez; Antônio Carlos Martins de Camargo
Applicant: Biosintética Farmacêutica Ltda ; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) ; Yara Cury
Deposit date: May 2005, 06
INPI register:
CN200580021319
IPC: C07K 7/08 C07K 14/46 C07K 1/16 A61K 38/10 A61K 38/00 A61P 25/04
Abstract

The present invention refers to analog compounds of peptides having the amino acid sequences SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3 or SEQ ID NO: 4, including analgesic peptides derived from snakes of species such as Crotalus durissus terrificus ; their uses in the treatment, diagnosis and prevention of painful conditions or mediated by opioid receptors, their pharmaceutical compositions and their methods of preparation and purification, including their uses in the identification of analgesic compounds.

Grantee:Vanessa Pacciari Gutierrez
Principal Investigator:Yara Cury
Institution: Secretaria da Saúde (São Paulo - Estado). Instituto Butantan
Support Opportunities: Scholarships in Brazil - Master