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EPITOPES, COMBINED EPITOPES, USE OF EPITOPES OR THEIR COMBINATION, COMPOSITION, USES OF THE COMPOSITION, ANTI- HIV-I PROPHYLACTIC VACCINES, THERAPEUTIC VACCINES, METHOD FOR THE IDENTIFICATION OF EPITOPES AND METHODS FOR TREATMENT AND PREVENTION
| Document type: | Patente |
| Inventor(s): | Edecio Cunha Neto; Jorge Elias Kalil Filho; Simone Gonçalves da Fonseca |
| Applicant: | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) ; Fundação Zerbini ; Universidade de São Paulo (USP) |
| Deposit date: | March 2008, 05 |
| INPI register: | |
| IPC: | C07H 21/04 A61K 39/21 |
Abstract
The present invention refers to new epitopes recognized by CD4+ T-lymphocytes. In addition, the present invention refers to the uses of such epitopes and their combinations, particularly in the treatment or prevention of disorders caused by the HIV-1 virus. The present invention also refers to a composition comprising said epitopes and the uses of said composition, particularly in the treatment or prevention of disorders caused by the HIV-1 virus. The present invention also refers to anti-HIV-1 prophylactic vaccines and therapeutic vaccines. Furthermore, the present invention refers to a method for the identification of epitopes and methods for treating or preventing an infection caused by the HIV-1 virus.
| FAPESP's process: | 01/00729-3 - Identification of virological, genetic and immunological factors associated with the phenotype of HIV disease non-progression: a study of HIV virulence markers, CCR5 co-receptor genotyping and expression of broad panel of cytokines (cDNA microarrays) in peripheral blood samples of patients with HIV progressors and non-progressors followed up at Casa da AIDS [SIDA Healthcare Services] |
| Grantee: | Edecio Cunha Neto |
| Principal Investigator: | Edecio Cunha Neto |
| Institution: | Secretaria da Saúde (São Paulo - Estado). Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Instituto do Coração Professor Euryclides de Jesus Zerbini (INCOR) |
| Support Opportunities: | Regular Research Grants |
| Grantee: | Edecio Cunha Neto |
| Principal Investigator: | Edecio Cunha Neto |
| Institution: | Secretaria da Saúde (São Paulo - Estado). Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Instituto do Coração Professor Euryclides de Jesus Zerbini (INCOR) |
| Support Opportunities: | Research Grants - Support for Intellectual Property Rights and Licensing (PAPI/Nuplitec) |