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LUCIFERASE FROM MACROLAMPIS SP
| Office | WIPO |
| Document type: | Patent |
| Inventor(s): | Vadim Viviani |
| Applicant: | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Vadim Viviani |
| Year: | 2007 |
| Application Number: | PCT/BR2007/000018 |
| IPC: | C07K 14/435 C12N 15/12 |
Abstract
This invention refers to a product from the area of biotechnology made up of recombinant Luciferase from Macrolampis SP with bimodal bioluminescence and high sensitivity to changes in Ph - and temperature, as dual reporter gene that encodes a bioluminous protein for use in simultaneous biosensors of gene expression and intracellular pH variations, with concentrations of phosphate and divalent cations from heavy metals, and presence of ATP and as intracellular biosensor of changes in pH and other homeostatic conditions.
| FAPESP's process: | 05/00696-9 - Macrolampis sp luciferase as dual reporter gene in simultaneous biosensors of gene expression and changes in intracellular pH, phosphate concentrations and heavy metal divalent cations |
| Grantee: | Vadim Viviani |
| Principal Investigator: | Vadim Viviani |
| Institution: | Universidade Estadual Paulista (UNESP). Campus de Rio Claro. Instituto de Biociências (IB) |
| Support Opportunities: | Research Grants - Support for Intellectual Property Rights and Licensing (PAPI/Nuplitec) |