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METHOD FOR OBTAINING LIPID NANOSTRUCTURES, THUS OBTAINED LIPID NANOSTRUCTURES AND USE THEREOF
| Document type: | Patente |
| Inventor(s): | Patrícia Bento da Silva; Regina Célia Galvão Frem; Adelino Vieira de Godoy Netto; Antonio Eduardo Mauro; Ana Maria da Costa Ferreira; Fernando Rogério Pavan; Clarice Queico Fujimura Leite; Marlus Chorilli |
| Applicant: | Universidade Estadual Paulista (UNESP) |
| Deposit date: | July 2016, 22 |
| INPI register: | |
| IPC: | A61K 9/51 C07F 1/08 A61P 31/06 A61K 31/4409 A61K 9/107 |
Abstract
The present invention relates to a method for obtaining lipid nanostructures comprising copper-isoniazid compounds. In addition, the present invention relates to the lipid nanostructures comprising copper-isoniazid compounds obtained by the present method, and to the use thereof to prepare medicinal drugs against mycobacteria in general. In a preferred embodiment, the invention relates to the use of the lipid nanostructures comprising copper-isoniazid compounds obtained by the present method, preferably MEB-I3 and MEB-I1, to prepare medicinal drugs for the treatment of active and latent tuberculosis, respectively.
| FAPESP's process: | 11/22488-0 - Discrete metallosupramolecules and metal organic frameworks (MOFs): synthesis, characterization and properties |
| Grantee: | Regina Celia Galvao Frem |
| Principal Investigator: | Regina Celia Galvao Frem |
| Institution: | Universidade Estadual Paulista (UNESP). Campus de Araraquara. Instituto de Química (IQ) |
| Support Opportunities: | Regular Research Grants |