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ANALOG COMPOUNDS OF ANALGESIC PEPTIDES DERIVED FROM THE VENOM OF CROTALUS DURISSUS TERRIFICUS SNAKES, THEIR USES, COMPOSITIONS, METHODS OF PREPARATION AND PURIFICATION
| Office | EPO |
| Document type: | Patent |
| Inventor(s): | Yara Cury; Gisele Picolo; Katsuhiro Konno; Renata Giorgi; Patrícia Brigatte; Vanessa Pacciari Gutierrez; Antônio Carlos Martins De Camargo |
| Applicant: | Biosintética Farmacêutica Ltda; Cury, Yara; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) |
| Year: | 2005 |
| Application Number: | EP 20050738454 |
| IPC: | A61K 38/00 C07K 14/46 C07K 7/08 G01N 33/68 |
Abstract
The present invention refers to analog compounds of peptides having the amino acid sequences SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3 or SEQ ID NO: 4, including analgesic peptides derived from snakes of species such as Crotalus durissus terrificus ; their uses in the treatment, diagnosis and prevention of painful conditions or mediated by opioid receptors, their pharmaceutical compositions and their methods of preparation and purification, including their uses in the identification of analgesic compounds.
| Grantee: | Vanessa Pacciari Gutierrez |
| Principal Investigator: | Yara Cury |
| Institution: | Secretaria da Saúde (São Paulo - Estado). Instituto Butantan |
| Support Opportunities: | Scholarships in Brazil - Master |