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COMPOSIÇÃO DE CARREADORES LIPÍDICOS NANOESTRUTURADOS NATURAIS COM INSTRÍNSECA AÇÃO ANESTÉSICA

Document type:Patente
Inventor(s): Lígia Nunes de Morais Ribeiro; Eneida De Paula; Simone Ramos de Castro; Ludmilla David de Moura; Marcelo Lancellotti; Márcia Cristina Breitkreitz; Viviane Aparecida Guilherme Damasio; Gustavo Henrique Rodrigues da Silva; Andre Ricardo de Lima; Marcelo Ventura Rubio; Daniel Junior de Andrade; Ricardo Antonio Polanczyk; Felícia Pereira de Albuquerque; Mônica Pascoli; Leonardo Fernandes Fraceto
Applicant: Universidade Estadual de Campinas (UNICAMP) ; Universidade Estadual Paulista Júlio de Mesquita Filho (Unesp)
Deposit date: May 2020, 14
INPI register:
PCT/BR2020/050162
IPC: A61P 31/04 A61P 31/10 A61K 9/107 A61K 36/61
Abstract

(EN) The present invention relates to formulations including nanostructured lipid carriers. Specifically, the formulation claimed herein comprises natural nanostructured lipid carriers (NLC) with a strictly natural composition that enables the encapsulation of essential oils with a notably stable profile, maintaining homogenous size and mean diameter distribution after one year of monitoring at ambient temperature. This feature provides a plurality of intrinsic effects, with anaesthetic, bactericidal, antifungal and biopesticide actions against caterpillars, woodworm and mites, without requiring the encapsulation of synthetic active substances.

FAPESP's process: 14/25372-0 - Development of nanostructured lipid carriers encapsulating local anesthetics processed biopolymeric matrices for topical application at oral mucosa
Grantee:Lígia Nunes de Morais Ribeiro
Principal Investigator:Eneida de Paula
Institution: Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia (IB)
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 18/24814-0 - Metabolomics of nanoparticles lipid carriers loaded with local anesthetic in vitro
Grantee:Gustavo Henrique Rodrigues da Silva
Principal Investigator:Eneida de Paula
Institution: Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia (IB)
Support Opportunities: Scholarships abroad - Research Internship - Doctorate