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CHEMICALLY MODIFIED POLYNUCLEOTIDES AND METHOD FOR PRODUCING CHEMICALLY MODIFIED POLYNUCLEOTIDES
| Office | USPTO |
| Document type: | Patent |
| Inventor(s): | José Eduardo Krieger; Alexander Henning Ulrich; Arthur Andrade Nery; Vinícius Bassaneze |
| Applicant: | Universidade de São Paulo (USP). |
| Year: | 2016 |
| Application Number: | US 14/915,170 |
| IPC: | C12N 15/1048 C12N 15/115 |
Abstract
The present invention relates to chemically-modified polynucleotides of formula (I): 5′-CONS-SEQ.ID.n-CONS-3′ (I) containing one or more modified pyrimidines and at least one inverted nucleotide repeat, and to the method for producing the same.
| FAPESP's process: | 06/61285-9 - Molecular basis of differentiation of stem and neural progenitor cells |
| Grantee: | Alexander Henning Ulrich |
| Principal Investigator: | Alexander Henning Ulrich |
| Institution: | Universidade de São Paulo (USP). Instituto de Química (IQ) |
| Support Opportunities: | Research Projects - Thematic Grants |