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METHOD OF IDENTIFICATION AND QUANTIFICATION OF PROTEINS, ISOFORMS OF THE ANGIOTENSIN I CONVERTING ENZYME

OfficeDPMA
Document type:Patent
Inventor(s): Dulce Elena Casarini; Odair Marson; Frida Liane Plavnik; José Eduardo Krieger
Abstract

A method of detecting a predisposition for the development of a kidney lesion in an individual including detecting a presence of at least three angiotensin converting enzyme isoforms in an aliquot of fresh or concentrated biological fluids, cells or tissues obtained from the individual; and quantifying the presence of the at least three antiotension converting enzyme isoforms.


FAPESP's process: 02/13290-2 - Angiotensin I: converting enzyme isoform (90 kDa), potential genetic marker of hypertension: processing, molecular and functional characterization, and genetic segregation
Grantee:Dulce Elena Casarini
Principal Investigator:Dulce Elena Casarini
Institution: Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM)
Support Opportunities: Research Projects - Thematic Grants

Grantee:Dulce Elena Casarini
Principal Investigator:Dulce Elena Casarini
Institution: Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM)
Support Opportunities: Research Grants - Support for Intellectual Property Rights and Licensing (PAPI/Nuplitec)