| Office | CIPO |
| Document type: | Patent |
| Inventor(s): | Antonio Carlos Martins De Camargo; Mirian Akemi Furuie Hayashi; Fernanda Calheta Vieira Portaro; Juliano Rodrigo Guerreiro |
| Applicant: | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) |
| Year: | 2003 |
| Application Number: | CA 2507811 |
| IPC: | A61K 45/00 A61P 25/00 C07H 21/04 C07K 16/40 C12N 15/57 C12N 9/50 C12N 9/64 C12P 21/02 C12Q 1/37 G01N 33/53 G01N 33/68 |
An in vitro process based on the inhibition activity of the endooligopeptidase A (EOPA) enzyme inhibitor with JA-2; characterized by contacting the EOPA enzyme with N-[1-(R,S)-carboxy-3-phenylpropyl]-Ala-a-aminoisobutyric acid (Aib)-Tyr-p-aminobenzoate (JA-2), for inhibiting neuritis formation and for lowering the levels of lymphoproliferation.
| FAPESP's process: | 95/02850-1 - Proteolytic processing of bioactive peptides and toxins |
| Grantee: | Antonio Carlos Martins de Camargo |
| Principal Investigator: | Antonio Carlos Martins de Camargo |
| Institution: | Secretaria da Saúde (São Paulo - Estado). Instituto Butantan |
| Support Opportunities: | Research Projects - Thematic Grants |
| Grantee: | Mirian Akemi Furuie Hayashi |
| Principal Investigator: | Mirian Akemi Furuie Hayashi |
| Institution: | Secretaria da Saúde (São Paulo - Estado). Instituto Butantan |
| Support Opportunities: | Research Grants - Support for Intellectual Property Rights and Licensing (PAPI/Nuplitec) |