Office | CNIPA |
Document type: | Patent |
Inventor(s): | Antonio Carlos Fávero Caires; Claudia Bincoletto Trindade; Ivarne Luis Dos Santos Tersariol |
Applicant: | Antonio Carlos Fávero Caires; Claudia Bincoletto Trindade; Ivarne Luis Dos Santos Tersariol |
Year: | 2003 |
Application Number: | CN 03824724 |
IPC: | C07F 17/02 |
The present invention relates to cyclopalladium compounds and their analogs containing bis-diphenylphosphine-ferrocene coordinating ligands as inhibitors of the activity of peptides and enzymes, such as serine peptidases, cysteine proteases, metalloproteases and Enzymes of the endopeptidase family, some of which have been implicated in the growth and metastasis of malignancies such as thyroid tumors. An example of this compound is shown in the figure. These compounds regulate the immune system by acting on the aforementioned enzymes and participating in the insertion of DNA molecules.
Grantee: | Antonio Carlos Fávero Caires |
Principal Investigator: | Antonio Carlos Fávero Caires |
Institution: | Universidade de Mogi das Cruzes (UMC). Centro de Ciências Exatas e Tecnologia |
Support Opportunities: | Research Grants - Young Investigators Grants |
Grantee: | Andrea Licia de Almeida Oliveira |
Principal Investigator: | Andrea Licia de Almeida Oliveira |
Institution: | Universidade de Mogi das Cruzes (UMC). Campus da Sede Mogi das Cruzes |
Support Opportunities: | Research Grants - Support for Intellectual Property Rights and Licensing (PAPI/Nuplitec) |