Abstract
The Oropouche virus (OROV) is a member of Bunyaviridae family, and the second most common cause of arboviral disease in Brazil, but its pathogenesis is largely unknown. OROV causes apoptosis of infected cells, both in vitro and in vivo. Preliminary lab results show that the non-structural protein NSs of OROV induces apoptosis in eukaryotic cells. This project aims to understand the mechan…