Paolo Bartolini

• Abstract

  The "Pituitary Hormones Research Group" at the Biotechnology Center of IPEN-CNEN / São Paulo has already published several works on techniques of Gene Therapy of growth, which is based on the injection of human (hGH) or mouse growth hormone (mGH) genes in the muscle of dwarf mice, followed by electroporation. In parallel, the same Group dedicated to the cloning, expression and characteriz…

  preliminary studies directed to the application of growth hormone gene therapy to Arapaima gigas, AP.R

• Abstract

  The common gonadotrophic hormone alpha-subunit (GTHa) has been previously isolated by our research group from A. gigas pituitaries; in the present work the cDNA sequences encoding FSHB- and LHB-subunits have also been isolated from the same species of fish. The FSHB-subunit consists of 126 amino acids with a putative 18 amino acid signal peptide and a 108 amino acid mature peptide, while …

  Molecular cloning and characterization of pirarucu (Arapaima gigas) follicle-stimulating hormone and luteinizing hormone b-subunit cDNAs, PUB.ART

• Abstract

  The goal of the present Project, whose Phase-1 will be completed in January 31st 2017 and whose partial Technical Report (first 6 months) has been already submitted to FAPESP, is the national synthesis and characterization of recombinant human bone morphogenetic protein-2 (rhBMP-2). During Phase-1, in agreement with the submitted proposal of technical viability, for the first time the per…

  Expression, purification and characterization of bone morphogenetic protein (BMP-2) for application in composites biomaterials with poly(E-caprolactone), AP.PIPE

(Only some records are available in English at this moment)

• Expression, purification and characterization of bone morphogenetic protein (BMP-2) for application in composites biomaterials with poly(E-caprolactone), BP.PIPE
• Expression, purification and characterization of bone morphogenetic protein (BMP-2) for application in composites biomaterials with poly(e-caprolactone), BP.PIPE