Abstract
Introduction: Nonsteroidal anti-inflammatory drugs (NSAIDs) are effective in reducing postoperative pain. The new COX-2 selective NSAIDs were developed to reduce the undesirable effects with similar analgesic efficacy to conventional NSAIDs. Parecoxib is the only COX-2 selective inhibitor available for parenteral use. By inhibiting the production of prostaglandins, may contribute to the d…