CV Lattes
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Universidade de São Paulo (USP). Faculdade de Odontologia (FO) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Holding a BDS degree from the Dental School of University of Sao Paulo (USP), Brazil, Tathyane has obtained her PhD degree in Oral Diagnosis in the Department of Oral Medicine of the same institution, with active participation in the Oral Medicine outpatient service in Hospital das Clínicas in Sao Paulo and in the diagnostic service in the department of Oral Pathology at USP for seven years. Currently holds a Post-doctoral Fellow position at the Department of Stomatology at USP, investigating the innervation during the development of salivary glands. Since 2013 she has been performing important research collaboration at the Dental Institute of King's College London, UK, as visiting PhD student funded by CNPq and also as visiting Post-Doc Fellow funded by FAPESP. Particularly interested in salivary glands, her main research focus at the moment is on development and regeneration of human and murine salivary glands. (Source: Lattes Curriculum)
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Human salivary glands are essential structures for the production and secretion of saliva, which reaches the oral cavity through the luminal space of salivary ducts. The process of lumen expansion has been recently reported to be required for the duct formation during glandular morphogenesis. It has been reported that this process depends on autonomic neuronal stimulation, which activates…
Salivary glands are responsible for secreting saliva and therefore contribute to the maintenance of the oral cavity homeostasis. Permanent glandular dysfunctions caused by radiotherapy, inflammatory diseases and genetic disorders commonly increase the risk of infections in oral mucosa and teeth surface, also affecting physiological oral functions as speech, mastication and taste, directly…
To date it is well known that the presence of autonomic nerves is required for proper development of salivary glands. In particular, it has been extensively reported that the parasympathetic nerves have an essential role during mouse gland development, maintaining the epithelial progenitor cells in an undifferentiated state. The role of the sympathetic nerves in turn has been correlated t…
Salivary glands secrete saliva, which is essential to the maintenance of oral health. Permanent salivary gland dysfunction mostly caused by radiotherapy, inflammatory diseases and congenital syndromes, frequently affects physiological oral functions, such as speech, taste and mastication, while also increases the risk of caries and oral mucosa injuries. The current treatments available ar…
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