Abstract
The rare but recurrent chromosomal translocation t(10; 11)(p13; q14), which results in the CALM/AF10 fusion gene, is found in patients with Acute Lymphoid Leukemia (ALL) and Acute Myeloid Leukemia (AML) or Acute Leukemia of Ambiguous Lineage. Leukemias harboring CALM/AF10 oncogene are associated with poor response to treatment and shorter disease-free survival and overall survival. These …