graduation at Ciencias Biologicas from Universidade Presbiteriana Mackenzie (1999), master's at Veterinary Medicine from Universidade de São Paulo (2002) and doctorate at Veterinary Medicine from Universidade de São Paulo (2006). Has experience in Veterinary Medicine, acting on the following subjects: antinocicepção, inflamação, hiperalgesia, farmacologia da dor inflamatória and peptídeo mrp-14. (Source: Lattes Curriculum)
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Chronic pain imposes a significant personal and economic burden, affecting over 30% of people worldwide, according to some studies. Unlike acute pain, chronic pain can be better considered a disease, with treatment and psychological implications. Pain can be categorized as nociceptive (from tissue injury), neuropathic (from nerve injury), or nociplastic (from a sensitized nervous system),…
Opioides have an addictive effect generate tolerance upon prolonged use causing unwanted side effects. Thus, there is a great need to search for new analgesic substitutes. To this end, understanding the signaling pathways that lead to pain can help develop new non-opioid analgesics. Inflammatory pain begins with the secretion of nerve growth factor (NGF) and activation of its high affinit…
Herpetic (HN) and postherpetic (PHN) neuralgia characterize herpes zoster pain, as burning, spontaneous pain, allodynia, and hyperalgesia. Although the literature indicates inflammatory and neuropathic processes as causes, the mechanisms described are still imprecise, and animal models for the study of HP and PHN are incomplete regarding central and peripheral sensitization in the nervous…
Diabetic neuropathy (DN) is one of the most common complications of diabetes, affecting about 50% of diabetic patients. Among the various symptoms of DN, the development of chronic pain, which mainly affects the extremities, is manifested as exacerbated responses to noxious stimuli (hyperalgesia) and pain in response to mild or non-painful stimuli (allodynia). Conventional treatments avai…
Peripheral neuropathy (PN) caused by diabetes mellitus is one of the most common complications of diabetes, affecting about 50% of patients with the disease. Among the many symptoms of NP, stands out the development of chronic pain, which affects mainly the extremities, presenting itself as exacerbated responses to noxious stimuli (hyperalgesia) and as pain in response to light or not pai…
(Only some records are available in English at this moment)
Opioides have an addictive effect generate tolerance upon prolonged use causing unwantedside effects. Thus, there is a great need to search for new analgesic substitutes. To this end,understanding the signaling pathways that lead to pain can help develop new non-opioidanalgesics. Inflammatory pain begins with the secretion of nerve growth factor (NGF) andactivation of its high affinity re…
Rheumatoid arthritis (RA) is an inflammatory disorder characterized by swelling and pain, as well as the destruction of synovial joints, which can lead to severe disability and premature death. Patients with RA experience intense and constant pain, as well as stiffness in joints, including wrists, proximal interphalangeal joints, and metacarpophalangeal joints. The pain associated with RA…
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive loss of memory with impaired cognitive functions. The two subtypes are familial AD, influenced by a genetic mutation with subsequent metabolism / abnormal extracellular deposition of the beta amyloid peptide (bA) and collapse of the cytoskeleton by hyperphosphorylation of the tau protein in the hippocamp…
(Only some records are available in English at this moment)
Diabetes Mellitus (DM) affects about 425 million people worldwide. These patients are often afflicted with lower extremity ulcers which account for about 60% of non-traumatic lower limb amputations. This results in high morbidity and mortality, with a significant loss in quality of life and socioeconomic impact. Conventional treatment for diabetic wounds is restricted to bandages and debr…
Neuropathic pain is one of the most rebellious conditions to the antalgic treatment, making the search for new effective therapies extremely urgent. Insular cortex is a new potential target for neuromodulation once it is closely involved in central pain integration and modulation and it is deeply affected in neuropathic pain states. We have recently demonstrated that electrical stimulatio…
| 2 / 2 | Ongoing grants |
| 6 / 5 | Completed research grants |
| 17 / 13 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 27 / 22 | All research grants and scholarships |
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CV Lattes
ORCID