CV Lattes
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Universidade Estadual Paulista (UNESP). Campus Experimental do Litoral Paulista. Instituto de Biociências (IB-CLP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Marine Biology and Coastal Management from Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP) (2013) and direct doctorate in Science from Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP) (2019) and sandwich PhD from King's College in London, United Kingdom (2018). Has experience in biochemistry, microbiology, genetics, evolution, bioinformatics, molecular and structural biology. (Source: Lattes Curriculum)
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L-asparaginases (L-ASPases) are important bacterial biopharmaceuticals used to treat Acute Lymphoblastic Leukemia (ALL), since this tumor type is dependent of asparagine availability of extracellular asparagine (Asn). Bacterial L-ASPases are able to hydrolyse efficiently Asn in Aspartic acid (Asp) and ammonia (NH3), thus reducing the Asn availability for tumor cells and inducing apoptosis…
Peroxiredoxins (Prx) are antioxidant proteins capable of decompose hydrogen peroxide, organic peroxides and peroxynitrite, using highly reactive cysteines present in their active sites to achieve reductions. Most of the Prx are found on the obligatory dimer form and after peroxide reduction, the Prx cysteines form a disulfide bond between two monomers (intermolecular), wich needs to be re…
Bacterial asparaginases (ASNase) are high molecular weight tetrameric enzymes (~140kDa) used as therapeutic proteins for treatment of acute lymphoblastic leukemia (ALL), since some tumor cell types are dependent on the availability of extracellular L-asparagine. Bacterial ASNase efficiently hydrolyzes aparagine (L-Asn) into aspartic acid (L-Asp) and ammonia, decreasing the source of L-Asn…
| 2 / 2 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 3 / 3 | All Scholarships |
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