Abstract
The electrotransfer of plasmid DNA containing the Genes for Human (hGH) or Mouse (mGH) growth hormone has been used by our group. For these studies of in vivo gene therapy, two animal models of GH deficiency, the dwarf (lit/lit) and immunodeficient dwarf (lit/scid) are used. With respect to the hGH gene, sustainable circulating levels of the hormone were obtained during 60 days, and a bod…