CV Lattes
Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Biomedical Sciences from Universidade Federal de São Paulo (2013). Has experience in Molecular Biology, acting on the following subjects: melanoma, DNA methylation, malignant transformation, methylome, RNA-seq. Graduate student at Unifesp - Ontogeny and Epigenetics laboratory, with experience of visiting PhD in Weill Cornell Medicine - NY. (Source: Lattes Curriculum)
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In our laboratory a murine melanocyte malignant transformation model was developed when submitting a non- tumorigenic melanocyte cell line, melan-a cells, to a sequential cycles of anchorage blockade. Along melanoma progression alterations in epigenetic marks, homocysteine content and increased reactive oxygen species (ROS) levels was showed. We have shown that increased ROS regulates glo…
The metacyclic trypomastigotes of Trypanosoma cruzi express two major surface glycoproteins called GP90 and GP82 that bind to mammalian cells through specific host receptors. The expression of GP90 protein correlates inversely with the invasive capacity of Trypanosoma cruzi, while the GP82 promotes the penetration of metacyclic forms into host mammalian cells. It has been suggested that t…
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