CV Lattes
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Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Post-doctorate in Center for Regenerative Medicine, Heart Institute, Department of Internal Medicine, University of South Florida, Morsani College of Medicine, USF-USA (2023-present). Ph.D. in Systems Biology from the Institute of Biomedical Sciences at the University of São Paulo, USP-Brazil (2020), with a Sandwich Ph.D. at Harvard Medical School/Boston Children's Hospital (2018-2019) - USA. Master of Science in Morphofunctional Sciences from the University of São Paulo, USP-Brazil (2014). Specialist in Exercise Physiology: Exercise Prescription from the Gama Filho University, UGF-Brazil (2009). Holds a bachelors degree in physical education from the Adventist University Center of São Paulo, UNASP-Brazil (2007). Experienced in cellular bioenergetics processes focusing on molecular alterations and pharmacological therapy, skeletal muscle, satellite cells, exercise physiology, ALDH2, heart failure, and necroptosis. (Source: Lattes Curriculum)
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Skeletal muscle satellite cells are stem cells located between basal lamina and the sarcolemma of the muscle fiber. Once activated, these mononuclear progenitor cells are capable of triggering a cellular reprogramming resulting in proliferation, renewal and differentiation of these cells in myoblasts. Considering the different energetic demands of the processes described above, the metabo…
Over the last years, the pathophysiology of cardiovascular disease has been associated to the formation and accumulation of oxidative stress-mediated aldehydes, which are highly cardiotoxic and contribute to the onset and / or aggravation of cardiovascular diseases. Among the various aldehydes accumulated in the heart, 4-hydroxy-2-nonenal (4-HNE), originated from the oxidation of inner mi…
Satellite cells are skeletal muscle stem cells essential for muscle regeneration. The activation of satellites cells is regulated by a series of transcription factors such as Pax7, Myf5, Myod, Myogenin. These factors regulate the myogenic identity of the cells in both proliferation and differentiation states. Oxidative metabolism and reactive oxygen species (ROS) play an important role in…
| 2 / 2 | Completed scholarships in Brazil |
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