Abstract
Mangiferin is a major component of M. Indica (Mango) has shown antioxidant and neuroprotective effect in a model of glial and neuronal damage. Studies suggest that mangiferin is able to limit the formation of free radicals to and production of prostaglandins (PGs) by reducing the synthesis of COX-2 in microglia cells. Also, mangiferin inhibits the chemotactic activity of neutrophil-mediat…