Abstract
The high incidence and mortality of hepatocellular carcinoma (HCC), as well as the limited treatment and poor prognosis of this disease make it important to adopt measures such as chemoprevention. Tributyrin (TB), a prodrug of butyric acid (BA) is a bioactive compound found in foods such as honey and milk. TB reduced the incidence and size of preneoplasic lesions and also induced apoptosi…