Abstract
Introduction: Multiple endocrine neoplasia type 2 (MEN2) is an autosomal dominant disease caused by germline RET mutation, which runs with medullary thyroid carcinoma (MTC), pheochromocytoma (Pheo), and hyperparathyroidism. The MTC is a malignant neoplasm, poorly responsive to chemo / radiotherapy, which develops already in the 1st decade of life. Thus, prophylactic thyroidectomy is indic…