Abstract
Inflammmatory bowel diseases (IBD) like Crohn's disease are characterized by Th1 and Th17 exacerbated inflammatory response besides a lack of regulation by regulatory T cells (Tregs). Chronic stress is a risk factor for IBD development while the endocrine system may also play a regulatory role by producing glucocorticoids (GC) which are anti-inflammatory mediators that may induce Treg dif…