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Jayme Augusto de Souza-Neto

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Universidade Estadual Paulista (UNESP). Campus de Botucatu. Faculdade de Ciências Agronômicas (FCA)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

Dr. Jayme Souza-Neto holds a bachelor degree in Biology from Northern Rio de Janeiro State University (UENF, 2002) and PhD in Genetics from São Paulo State University Institute of Biosciences (IBB/UNESP, 2006). Dr. Souza-Neto has a Postdoctoral training at the Johns Hopkins Bloomberg School of Public Health (2008-2011) in the field of vector-pathogen interactions functional genomics. He currently is an Assistant Professor at the Department of Bioprocesses and Biotechnology and coordinates the Vector Functional Genomics & Microbiology Laboratory (Vectomics) from the UNESP Institute of Biotechnology (Botucatu). Dr. Souza-Neto is also affiliated to Keele University and Imperial College London as Visiting Lecturer and Visiting Researcher, respectively. Dr. Souza-Neto studies vector-pathogens interactions focusing on the identification of genes and bacteria to block the transmission of human pathogens. He coordinates research activities with British groups under the FAPESP-Keele and FAPESP-Imperial college cooperative agreements. His work has been published in prestigious scientific magazines such as Nature, Science, PNAS and PLoS journals. He is a FAPESP Young Leader (STS forum 2014) and Young Investigator Awardee since 2013, actively acting in national and British funding agencies? scientific panels (FAPESP, Confap, MRC-UK, Newton Fund). Dr. Souza-Neto is a member of the São Paulo State Zika Network and the coordinator of the UNESP Arboviroses Network. Since 2016 Dr. Souza-Neto integrates the Board of the Zika Research Program under the FAPESP?s Board of Scientific Directors. (Source: Lattes Curriculum)

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FAPESP Week France 2019 | Jayme Augusto de Souza-Neto. From mosquito’s genes to microbes and more: current research and approaches to tackle vector-borne diseases

Published in Nov. 21, 2019 - Agência FAPESP. Mosquitos are the most abundant and relevant insect vectors of human pathogens across the entire world. Together, the diseases caused by pathogens such as the arboviruses dengue, Zika and chikungunya, and Plasmodium parasites affect hundreds of millions of people worldwide and put at risk more than half of the world population, mainly around the tropics. The insect midgut is the first and most critical site of interaction between mosquito vectors and human pathogens. In this organ, the pathogen must overcome the mosquito’s innate immunity and gut microbiota in order to be successfully transmitted. My group is particularly interested in the mosquitoes Aedes aegypti, the main arboviral vector in the world, and Anopheles darlingi, the main malaria vector in South America. We are focusing on understanding the cross-talk between human pathogens and the mosquito’s gut microbiota, and the influence of the vector innate immunity in such process. Unraveling these mechanisms are pivotal for a better understanding of vector-pathogen interactions and for the development of new tools to curb disease transmission. Read more about FAPESP Week France 2019: http://www.fapesp.br/week2019/france/
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