Dagmar Ruth Stach - Machado

• Abstract

  Molecular mechanisms responsible for periodontal disease (PD) and its worsening in type 1 Diabetes Mellitus (DM1) remain unknown. Cytokine profile and expression levels of collagenases,Mmp14, and tissue inhibitors were determined, as were the numbers of neutrophils and macrophages in combined streptozotocin-induced DM1 and ligature-induced PD models. Increased IL-23 (80-fold) and Mmp8expr…

  Sequential IL-23 and IL-17 and Increased Mmp8 and Mmp14 expression characterize the progression of an experimental model of periodontal disease in type 1 diabetes, PUB.ART

• Abstract

  Periodontal disease is characterized as a group of lesions in the tissues that surround and support teeth in their sockets, which can result in tooth loss. The main etiologic agent of periodontal disease is bacterial plaque, but the host immune response determines disease susceptibility. Although the host response means to be protective, it initiates a cascade of events that can lead to i…

  Characterization of the inflammatory and immune mechanisms involved in periodontal disease in rats obese, AP.R

• Abstract

  In periodontal disease, extensive disorganization of the extracellular matrix promotes the loss of adhesion between the teeth and periodontium. A previous study suggested a reduction in the area occupied by collagen in the gingiva, during the first week of periodontal disease induction, however, the remaining fibers were more compact and thicker. Therefore, it was decided to investigate w…

  Changes in MMPs and inflammatory cells in experimental gingivitis, PUB.ART

• Abstract

  Periodontal disease is characterized a group of lesions in the tissues that surround and support teeth in their sockets, which can result in tooth loss. The main etiologic agent of periodontal disease is bacterial plaque, but the host response that determines disease susceptibility. Although the host response has meant to be protective, it initiates a cascade of events that can lead to im…

  Evaluation of cell migration and chemokine expression in the progression of periodontal disease in obese and normal mice., BP.IC
• Analysis of mechanisms involved in periodontal tissue destruction on obese and obese diabetic rats with experimental periodontal disease, BP.MS
• Avaliacion of Type I Diabetes Mellitus in migracion profile of inflammatory cells and cytokines during the induced Periodontal dissease progression., BP.IC

(Only some records are available in English at this moment)