CV Lattes
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Universidade de São Paulo (USP). Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP) (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduate at Bacharelado Em Química from Universidade Estadual Paulista Júlio de Mesquita Filho (1997) and ph.d. at Chemistry from Universidade Estadual Paulista Júlio de Mesquita Filho (2003). Has experience in Chemistry, focusing on Chemistry of the Natural Products, acting on the following subjects: rubiaceae, chimarrhis turbinata, gapdh, dpph and imers. (Source: Lattes Curriculum)
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The increasing interest in approaches that use fast and efficient separation and screening techniques to identify active molecules from natural extracts and combinatorial collections has been stimulated the development of new methods and integrated screening platforms that facilitate and reduce time-consuming to identify these molecules. With the proposal to develop new ligand screening m…
The identification of substances with biological activity in natural extracts or from synthetic collections is a crucial and complex step and promotes a growing interest in the use of fast and efficient techniques of separation and screening. Such a paradigm stimulates the development of new screening methods that facilitate and reduce the time spent in identifying these substances.Widely…
Several high-throughput assay strategies have been developed for the discovery of protein ligand; among them, frontal (FAC), Zonal (LZC) and nonlinear (NLC) chromatography with immobilized enzymes. The outstanding advantage of bioaffinity chromatography is the easy thermodynamics, kinetics and chemical ligand characterization, in an on-line hyphenated system. This project addresses the de…
(Only some records are available in English at this moment)
The identification of compounds which specifically bind the biological target of great importance in research for development of new drugs assisting in reducing the time and number of candidates. Efficient strategies have been developed and a very useful tool is the bioaffinity chromatography involves the immobilization of a target. This bonding agent may be a sequence of DNA, RNA, antibo…
The identification of substances with biological activity in natural extracts or synthetic collections is a crucial step and requires the use of fast and efficient techniques for separation and screening. This paradigm stimulates the development of new screening methods to facilitate and reduce the time taken to identify such substances. By employing chromatographic techniques, isolation …
According to the World Health Organization (WHO), leishmaniasis is a neglected disease that afflicts people in underdeveloped countries, and disfigures, stigmatizes and kills. Therefore, through a Special Research and Training Programme (TDR) the WHO aimed to eradicate this disease, which is currently treated with expensive and toxic drugs. Researchers have characterized and purified prot…
(Only some records are available in English at this moment)
Natural product extracts can be considered an invaluable source of biological active secondary metabolites. The screening of natural products for bioactive compounds has been clearly demonstrated to be a successful approach for the discovery of new drug leads. However, screening biological activities compounds from complex matrices as natural products is laborious, time consuming and cos…
Enzymes have excellent properties as activity, selectivity and specificity, which ensures its high application potential, but are limited due to the high cost and low stability in solution. With advances in technology and in an attempt to take advantage of all the catalytic properties of enzymes for longer, immobilization methods are an alternative to in vitro studies. If there is more th…
The identification of substances with biological activity in natural extracts or synthetic collections is a crucial step and requires the use of fast and efficient techniques for separation and screening. This paradigm stimulates the development of new screening methods to facilitate and reduce the time taken to identify such substances. By employing chromatographic techniques, isolation …
| 1 / 1 | Ongoing research grants |
| 5 / 5 | Completed research grants |
| 11 / 7 | Completed scholarships in Brazil |
| 3 / 3 | Completed scholarships abroad |
| 20 / 16 | All research grants and scholarships |
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