Abstract
STI1 (Stress Inducible Protein 1) was originally characterized as a co-chaperonin that interacts with heat shock proteins Hsp70 and Hsp90 and regulates its activity in the control of protein folding. However, recent studies demonstrate its broad functional versatility and show its mediation in neurotrophic effects in biological processes such as neuritogenesis, neuroprotection, developmen…