Abstract
The amino acid hypusine was first described in 1971, from bovine brain. Later, the hypusine was found in other mammalian tissues, like liver, kidney, muscle, and blood. In addition to being found in its free form, the hypusine is an amino acid residue present in eukaryotic translation initiation factor 5A (eIF5A). The eIF5A is the unique protein described that contains hypusine, produced …