Maria Lucia Zaidan Dagli

CV Lattes ResearcherID ORCID

Universidade de São Paulo (USP). Faculdade de Medicina Veterinária e Zootecnia (FMVZ) (Institutional affiliation from the last research proposal)
Birthplace: Brazil

graduate at Medicina Veterinária from Universidade de São Paulo (1983), master's at Medicina Veterinária from Universidade de São Paulo (1989) and ph.d. at Veterinary Medicine from Universidade de São Paulo (1994). Has experience in Veterinary Medicine, focusing on Anatomy Animal Pathology, acting on the following subjects: caes, conexinas, neoplasias, pfaffia paniculata and cães. (Source: Lattes Curriculum)

News published in Agência FAPESP Newsletter about the researcher

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Research grants

Ongoing (most recent)

Abstract
Metabolic dysfunction-associated steatohepatitis (MASH) is a highly prevalent liver disorder featured by steatosis, inflammation and fibrosis, with the latter being mainly mediated by hepatic stellate cells (HSCs). MASH frequently evolves towards hepatocellular carcinoma (HCC), yet the mechanisms underlying this process remain unclear. The hypothesis of this project is that communication …
Role of Panx1 channels and Cx43 hemichannels as new therapeutic targets in the paracrine signalling circuit between hepatic stellate cells and hepatocellular carcinoma cells established in metabolic dysfunction-associated steatohepatitis, AP.R
Abstract
Squamous cell carcinoma (SCC) is a highly aggressive and prevalent non-melanoma skin cancer (NMSC) in both humans and other animals. The main risk factor for SCC is ultraviolet radiation (UV), especially UVB, which induces direct damage to DNA, among other mechanisms. Skin carcinogenesis, and the development of SCC, consists of multiple stages, which makes it possible to interfere in the …
Exploring Connexin Mimetic Peptides in Strategies of Prevention and Treatment of Squamous Cell Carcinomas induced by UV radiation and other cutaneous neoplasms: in vitro and in vivo studies., AP.R

Completed (most recent)

RASS - Risk Assessment Summer School, AO.R
Abstract
Cancer epidemiology is a growing area in Veterinary Medicine. The Laboratory of Experimental and Comparative Oncology of the Department of Pathology at FMVZ-USP has also been dedicated to carrying out studies on the epidemiology of animal cancer. This is also one of the lines of research included in the CEPID proposal in Comparative and Translational Oncology, recently submitted and under…
Visiting Researcher from abroad to participate in research projects in cancer epidemiology in animals in the city of São Paulo and give lectures on the Vet-OncoNet and Vet-ICDO-canine 1 systems., AV.EXT
Abstract
Cancer epidemiology is a growing area in Veterinary Medicine. The Laboratory of Experimental and Comparative Oncology of the Department of Pathology at FMVZ-USP has also been dedicated to carrying out studies on the epidemiology of animal cancer. This is also one of the lines of research included in the CEPID proposal in Comparative and Translational Oncology, recently submitted and under…
Visiting Researcher from abroad to participate in research projects in the pathology of animal cancers in the city of São Paulo and to give lectures on the Vet-ICDO-canine 1 system., AV.EXT

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(Only some records are available in English at this moment)

Scholarships in Brazil

Ongoing (most recent)

Abstract
Connexins are transmembrane proteins that form gap junctions or nexuses, responsible for the direct exchange of solutes between adjacent cells. Intercellular communication through gap junctions is important for preserving tissue homeostasis. Connexins are normally located in cell membranes and changes in their expression and subcellular localization may be associated with pathological pro…
Evaluation of connexin expression and their subcellular localization in pancreatitis and endocrine and exocrine pancreatic neoplasias in dogs., BP.MS
Evaluation of connexin expression, their subcellular localization, and effects of treatment with connexin mimetic and non-mimetic peptides in vivo., BP.TT
Abstract
Oral mucosal melanomas (OMM) are very common and aggressive neoplasms in dogs. Treatment options for MMO include surgery, chemotherapy, radiotherapy and immunotherapy, however, relapses and metastases are frequent due to rapid evolution and multiple drug resistance (MDR). Therefore, new therapies are being researched and tellurium (Te) compounds have demonstrated effectiveness, one of the…
Evaluation of the in vitro and in vivo effect of tellurium (Te) compounds in therapy for canine oral mucosal melanoma, with and without association with carboplatin., BP.DD

See more Ongoing scholarships in Brazil

(Only some records are available in English at this moment)

Completed (most recent)

Evaluation of connexin expression, its subcellular localization, and effects of treatment with mimetic and non-mimetic peptides for connexins in vivo., BP.TT
Abstract
Cancer is considered a worldwide epidemic today. Breast cancer is the most prevalent neoplasm in women and also in dogs. Tumor cell lines from animal models are used in assays, such as the 4T1 murine breast tumor line, for testing with new medications. Recent studies demonstrate benefits of using dichloroacetate (DCA) and omeprazole (OMP) in the treatment of malignant neoplasms. DCA has a…
Evaluation of the effects of sodium dichloroacetate and omeprazole on the 4T1 murine breast tumor: in vitro studies, BP.IC
Abstract
Breast cancer is an aggressive cancer that is among the leading causes of death in women. The biology of the breast tumor is complex, heterogeneous, with rapid tumor growth and high occurrence of metastasis, increasing the rates of morbidity and mortality if not diagnosed early. Research on the use of the mesenchymal stem cell (MSC) in cancer therapy has been carried out due to its innate…
Effect of canine mesenchymal stem cells derived from adipose tissue on 4t1 mammary tumor growth, BP.IC

See more Completed scholarships in Brazil

(Only some records are available in English at this moment)

Scholarships abroad

Completed (most recent)

Abstract
Metastatic breast cancer remains essentially incurable, highlighting the critical need for new therapeutic targets. Several experiments in vivo have investigated breast cancer progression towards metastasis. In certain cancers the trigger for cancer development are oncogenes expression or mutation that change the normal physiology of cells, and causing the cancer phenotype of a single cel…
Role of connexins during breast tumor development: study in tritransgenic mice and 3D primary cell culture, BE.EP.PD

Virtual Library in numbers * Updated data on September 13, 2025

Total / Available in English

2 / 2	Ongoing grants
61 / 30	Completed research grants
4 / 4	Ongoing scholarships in Brazil
73 / 25	Completed scholarships in Brazil
2 / 1	Completed scholarships abroad
142 / 62	All research grants and scholarships

Associated processes

Most frequent collaborators in research granted by FAPESP

Keywords used by the researcher

Agronomical Sciences Health Sciences Interdisciplinary Subjects Medicine Veterinary Medicine

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