CV Lattes
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Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Pharmacy-Biochemistry from the Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (1999-2003), Master's (2003-2005) and Ph. Professor (2016) in Pharmacology at the Faculty of Medicine of Ribeirão Preto, University of São Paulo. Sabbatical (Visiting Professor) at Harvard Medical School, Department of Immunology as part of the CAPES/Harvard Young Visiting Professor program. He was an Affiliate member of the Brazilian Academy of Sciences. He has been awarded national and international scientific awards, including the prestigious 2020 Patrick D. Wall Young Investigator Award for Basic Science from the International Association for the Study of Pain (IASP). He is currently an Full Professor of Pharmacology at FMRP-USP. Academic editor of international journals such as Communications Biology, Brain Research, Frontiers in Pharmacology and Inflammation Research. Has experience in Pharmacology, with emphasis on Pharmacology of Inflammation and Pain, working mainly on the following topics: Neurobiology of inflammatory and neuropathic pain and Molecular mechanisms involved in the effects of analgesics. (Source: Lattes Curriculum)
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Nociceptive/physiological pain is one of the main protective mechanisms that animals have developed to deal with the environment (external and internal), without which, the survival of the being is threatened. On the other hand, in certain situations, functional changes in the nociceptive system lead to the development of pain considered pathological, including neuropathic pain. Neuropath…
Inflammatory diseases are a complex and heterogeneous group of diseases that affect more than 10% of the word population. The current options for the treatment of these diseases are still limited and in some cases, inefficient due to limited understanding of the mechanisms underlying these diseases. The development of translational research by a center that can generate scientific knowled…
Arboviruses represent a serious public health problem which hasWorsened in recent years due to the insertion of new viruses into highlysusceptible. The concomitant circulation of different viruses results in a lower load thanhealth systems, which is unprepared to deal with the different clinical formsthese infections. It is known that arbovirus infection usually results in a February fram…
This decade begins with a worldwide health emergency, the new coronavirus pandemic, cause of severe acute respiratory syndrome 2 (SARS-CoV2). Until this date, there are more than 900,000 positive cases that have resulted in more than 44,000 deaths in 180 countries. In view of these epidemiological data, strategies are needed to contain the transmission of the virus and mainly effective al…
(Only some records are available in English at this moment)
neuropathic pain is a disease of the somatosensory system that can result from different etiological factors such as mechanical, biological, metabolic, or chemical insults. Chemotherapeutic agents used to treat cancer can cause neuropathic pain (CINP) due to their neurotoxicity to primary sensory neurons, causing aberrant functioning of these cells and leading to long-lasting pain in canc…
Neuropathic pain is a type of chronic pain caused by an injury or disease of the central or peripheral somatosensory nervous system. Pharmacological treatment for neuropathic pain is quite limited. Although the response to existing treatments may be effective at first, they become flawed over time and cause unwanted side effects. Hydroxycarboxylic acid receptor 2 (HCAR2), also known as GP…
Astrocytes are the glial cells present in greatest quantity in the Central Nervous System (CNS) and have been increasingly described as important components in homeostatic and pathological conditions. Among some situations, these cells are known to play a major role in the development of neuroinflammatory diseases. Given the highly energetic profile of astrocytes, these cells have the abi…
(Only some records are available in English at this moment)
Inflammatory diseases represent a complex and heterogeneous group of disorders that cause morbidity and mortality worldwide. In this context, the Center for Research in Inflammatory Diseases (CRID/USP) has a unique role. The discovery of multiple molecular targets for these diseases is an example of their work. Some of these targets are the proteins: hPKM2, hKMO, hIDO-1 and hPAD4. In HTS …
(Only some records are available in English at this moment)
Chronic pain, lasting over three months, significantly affects quality of life, with neuropathic pain being one of its most common forms. This condition results from injuries or diseases affecting the nervous system and is challenging to treat due to the limited effectiveness of available analgesics. Nerve injury leads to biochemical changes that contribute to peripheral and central sensi…
Once considered passive anatomical barriers, the meninges have emerged as an important regulatory niche for immune responses in the central nervous system. Recent studies have revealed that the meninges harbor various lymphoid and myeloid cells. Among this large repertoire of immune cells, type 2 innate lymphoid cells (ILC2s) stand out for their fundamental role in modulating local proces…
Macrophages serve multiple functions including immune regulation, tissue homeostasis, and morphogenesis. These myeloid cells are a diverse group of cells that represent an important population located at strategic points and borders between the central nervous system (CNS) and peripheral nervous system (PNS). In the dorsal root ganglia (DRG) and the trigeminal ganglion, which contain the …
Neuropathic pain is a disease of the somatosensory system that can result from different etiological factors such as mechanical, biological, metabolic, or chemical insults. Chemotherapeutic agents used to treat cancer can cause neuropathic pain (CINP) due to their neurotoxicity to primary sensory neurons, causing aberrant functioning of these cells and leading to long-lasting pain in canc…
Microglia and astrocytes are the most extensively studied cells beyond neurons in the CNS and are in a dynamic communication in healthy and diseased brains. Chronic neuroinflammation can cause synaptic dysfunction and neuronal death, being a common feature of neurodegenerative diseases, such as Alzheimer's disease (AD). In the past years, it has become evident that metabolism regulates th…
(Only some records are available in English at this moment)
| 2 / 2 | Ongoing grants |
| 6 / 6 | Completed research grants |
| 4 / 4 | Ongoing scholarships in Brazil |
| 40 / 36 | Completed scholarships in Brazil |
| 2 / 2 | Ongoing scholarships abroad |
| 8 / 8 | Completed scholarships abroad |
| 62 / 58 | All research grants and scholarships |
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