CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus Diadema. Instituto de Ciências Ambientais, Químicas e Farmacêuticas (ICAQF) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's degree in Chemistry from Mackenzie University (1992), a master's degree in Organic Chemistry from the University of São Paulo (1996) and a doctorate in Organic Chemistry from the University of São Paulo (2000). Currently is a full professor at the Federal University of São Paulo UNIFESP-Campus Diadema. Coordinate the Postgraduate Program in Chemical Biology. Since 2023, has participated in the CEPID-ARIES on microbial resistance, contributing to the prospecting of new antimicrobial agents. Has been a member of the ResNet NPND (Universität Münster - Germany) research network on neglected diseases since 2020. Has experience in the field of Chemistry, with an emphasis on Chemistry of Natural Products, working mainly on the following topics: Bioprospecting of plants and their associated endophytic fungi, through of a metabolomic approach using UHPLC-HRMSMS techniques associated with molecular networks for the isolation of bioactive secondary metabolites in models of antiparasitic, antitumor and antimicrobial activity in addition to basidiomycete fungi and polysaccharides with immunomodulatory activity. Integration of metabolomics and genomics to identify biosynthetic gene clusters of bioactive metabolites. (Source: Lattes Curriculum)
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Fungi and bacteria are widely distributed in nature and are capable of surviving in diverse environments, in addition to representing an important source of natural products. Many of these metabolites have diverse biological activities, and several of them have become medicines used in therapy. Additionally, the rise of omics sciences is the result of the advancement of analytical techniq…
The present project intends to advance the frontier of knowledge between metabolomics and genomics in order to search for secondary metabolites with antitumor potential from endophytic fungi and basidiomycetes. Thus, it is proposed to perform the dereplication of extracts obtained from basidiomycete fungi as well as extracts obtained from the fermentation of endophytic fungi associated wi…
The present project aims to evaluate the antimicrobial, antitumor and antiparasitary potential of plant species, endophytic fungi associated with these species and basidiomycete fungi that will be collected in the Atlantic Forest of the state of São Paulo aiming at the isolation of special bioactive metabolites. In this way, species belonging to the various plant families, associated endo…
(Only some records are available in English at this moment)
The study of basidiomycetes, mushrooms also known as macroscopic fungi, as a biosprospective resource of medicinal products, has developed the interest of a large amount of researches across the world. This interest is due to the production of a large amount of bioactive substances, from primary and secondary metabolism. These substances from fungi metabolism has been extracted and studie…
Visceral leishmaniasis and Chagas disease, are important neglected diseases in underdeveloped and developing countries, caused by Leishmania sp and Trypanosoma cruzi respectively. The treatment against these two diseases has high toxicity, leading to the occurrence of serious adverse effects. That raises the need for research and development of new drugs, and natural products have great p…
Plants are an important source of bioactive natural products showing several pharmacological activities including antitumor, anti-inflammatory, antibiotic and anti-parasitic. The present work aiming to evaluate the therapeutically potential of Baccharis uncinella, specie belonged to Asteraceae family, in the treatment of leishmaniosis and Chagas' disease. In this way crude extracts will b…
| 1 / 1 | Ongoing grants |
| 8 / 5 | Completed research grants |
| 6 / 3 | Completed scholarships in Brazil |
| 15 / 9 | All research grants and scholarships |
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