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Universidade de São Paulo (USP). Escola de Artes, Ciências e Humanidades (EACH) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Luiz Paulo Moura Andrioli in research grants and scholarships supported by FAPESP.
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Knowledge of the molecular mechanisms responsible for differential transcription, especially the way in which transcription factors act, is still minimal. Our group addresses this question by investigating the segmentation cascade model system that specifies the anterior-posterior axis of the Drosophila melanogaster body. We recently published articles focusing on the initial levels of th…
This proposal aims to study gene expression regulation and probe evolutionary mechanisms involved in the segmentation of dipterans. Our main goal is to investigate the transcriptional regulation of the segmentation cascade of Drosophila melanogaster. Our focus is the anterior portion of the syncytial blastoderm of Drosphila where the expression domains of gap genes are partially overlappi…
The aim of this proposal is to study the molecular aspects of the segmentation cascade in the anterior regions of the embryos of two species of dipterans, the Drosophila melanogster model and the sciarid fly Trichosia pubescens. For Drosophila, we aim to investigate the transcriptional regulation of the modular promoters of the pair-rule genes. In the anterior regions of Drosophila, corre…
Differential transcription is mainly responsible for the process of cellular differentiation, and the Drosophila segmentation cascade constitutes a model system in transcriptional studies. In recent years, our laboratory has been investigating the hypothesis that a combined activity of transcription repressive factors, in addition to delimiting the expression contours of target genes, pro…
Cellular differentiation relies on differential transcription of genes. However, many fundamental questions about transcription control remains unsolved, for instance, which properties establish the interaction between transcription factors and their respective binding sites in vivo? Or, how does the interaction between transcription activator and repressor factors in gene regulatory regi…
This proposal is linked to the FAPESP research grant 2014/14318-5. In the lab we study the gene expression regulation of the segmentation cascade of Drosophila melanogaster. More precisely, we investigate the action of maternal and gap transcription factors in the regulation of the anterior most stripes of the pair-rule seven striped pattern. We test the hypothesis that there are several …
| 1 / 1 | Ongoing grants |
| 4 / 2 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 10 / 3 | Completed scholarships in Brazil |
| 1 / 0 | Completed scholarships abroad |
| 17 / 7 | All research grants and scholarships |
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