Dr. Costa is a biologist from the University of Brasília (1994) with a MS and PhD in Microbiology, Immunology and Parasitology from the Federal University of São Paulo (1998, 2001) and lecturer in Parasitology at University of Campinas (UNICAMP) (2011). He completed post-doctoral training at Institut Pasteur in France (2003). He is Full Professor at the UNICAMP Institute of Biology (IB), where he engages in translational research on tropical diseases, with emphasis in the understanding of immunopathological aspects of Malaria and Zika, as well as the discovery of new drugs. He was an advisor for International Relations at UNICAMP (2010-2012), coordinator for the graduate program in Genetics and Molecular Biology (CAPES 7) for the IB (2016-2018) and was a member of the CNPq Advisory Committee for Microbiology and Immunology (2017-2018). He is currently the Coordinator of International Relations for IB and Academic Editor of the scientific journals PLoSOne and Frontiers in Immunology. He is a CNPq research fellow level 1C (Source: Lattes Curriculum)
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In this collaborative project with the University of Glasgow, we propose, for the first time, an analysis of an overlooked but critical and still neglected aspect of the cycle of the parasite Plasmodium vivax (Pv), referring to the infection of this pathogen in the potential niches hematopoietic. Here, we will systematically investigate Pv infection in one of the main hematopoietic niches…
Malaria caused by Plasmodium vivax is the most widely distributed Malaria form in the world. Worldwide, 2.5 billion people are at risk of Plasmodium vivax infection, with 8.5 million cases worldwide in 2015. Brazil, together with Venezuela, is the leader in cases in the Americas, 99.5% of which are reported in the region called Legal Amazon. Currently more than 85% of cases in Brazil are …
The arrival of COVID-19 in Brazil in March 2020, with its rapid dissemination, exponential growth of cases and the lethality of infected patients, has generated panic in the population, unstructured public and private health systems and negatively impacted the economy of Brazil and around the world. Although the search for an effective vaccine is urgent, its development should require at …
Malaria remains one of the leading causes of death by infectious diseases worldwide. In 2015, the WHO estimated 429,000 deaths from malaria. Around 99% of the deaths are caused by Plasmodium falciparum (Pf), which has become resistant to most conventional drugs. Therefore, there is an increased need to develop alternative treatment strategies. The partnership between Dr. Susanne Talcott a…
The current proposal aims to strengthen the scientific cooperation between UFG-GO and UNICAMP, through the host of Prof. Carolina Horta Andrade, as Visiting Researcher. The hosting of Prof. Carolina Andrade will attend two research projects, one Thematic and one Young Investigator (see attached summaries in SAGE) due to the complementary nature of these projects and the profile of Prof. A…
(Only some records are available in English at this moment)
Malaria remains a major public health problem worldwide. The causative agents of malaria, Plasmodium parasites, replicate asexually in red blood cells (RBCs) and data previously published support that there is an enrichment of parasites in the hematopoietic niches of the bone marrow (BM) and spleen due to the tropism of these parasites by immature reticulocytes that are present in this en…
Plasmodium vivax is the most geographically widespread Plasmodium species and also a cause of severe Malaria, which poses a major challenge for elimination in Malaria endemic regions. It is estimated that in 2019, Malaria reached 228 million people and killed about 405,000. Brazil is the leader in cases in the Americas, 99.5% of which are reported in the region called the Legal Amazon. Th…
(Only some records are available in English at this moment)
Malaria remains a global health problem. According to estimates by the World Health Organization in 2020, approximately 241 million cases and 627 thousand deaths were recorded. Among the species that cause human malaria, Plasmodium vivax is the species that has the highest geographic distribution in addition to being the most prevalent species outside the African continent. Brazil is the …
Malaria caused by Plasmodium vivax is the most widely distributed form of the disease in the world. Currently, 2.5 billion people are at risk of infection with P. vivax, and in 2015 there were 8.5 million cases worldwide. Brazil, together with Venezuela, is the leader in cases in the Americas, with 99.5% of these reported in the region called Legal Amazon and, currently, more than 85% of …
(Only some records are available in English at this moment)
With approximately 229 million cases and over 400 thousand deaths reported in 2019, malaria still imposes a heavy burden upon developing countries. One of the biggest challenges in fighting malaria is the selection and expansion of parasite strains resistant to available antimalarial drugs, which has already been reported even for frontline treatments such as artemisinin-based combined th…
Malaria is among the three infectious human diseases causing the greatest number of deaths worldwide, together with AIDS and tuberculosis. The use of antimalarials is essential for the containment of the disease and treatment of those infected. The frequent parasitic resistance to current antimalarials claims for the constant study and development of new chemical compounds capable of kill…
Studies on Plasmodium vivax biology and immunopathogenesis have long been neglected due to the relatively reduced pathology compared to P. falciparum malaria. Detection of all parasite stages in blood circulation also suggested absence of significant levels of tissue sequestration in P. vivax, further supporting the lack of severe symptoms. However, several recent observations have challe…
(Only some records are available in English at this moment)
| 2 / 2 | Ongoing research grants |
| 13 / 12 | Completed research grants |
| 4 / 4 | Ongoing scholarships in Brazil |
| 35 / 29 | Completed scholarships in Brazil |
| 6 / 6 | Completed scholarships abroad |
| 60 / 53 | All research grants and scholarships |
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