CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Araraquara. Faculdade de Odontologia (FOAr) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Associate Professor of the Department of Physiology and Pathology, School of Dentistry of Araraquara (FOAr), São Paulo State University (UNESP). Obtained the Bachelor in Pharmacy and Biochemistry (BPharm) degree from the State University of Londrina (2003), and M.Sc. (2006) and Ph.D. (2010) degrees (Physiology) from the University of São Paulo. He is research fellow (PQ) from CNPq. He has experience in the field of System Physiology, with emphasis in Respiratory Physiology, Cardiovascular Physiology and Neuroscience. His research seeks to elucidate how the brain coordinates respiration and cardiovascular function in different physiological (rest, high altitudes (reduction of oxygen partial pressure) and physical exercise] and pathological states (sleep-breathing disorders, hypertension, neurological syndromes). Using different experimental techniques, in collaboration with other researchers from Brazil and abroad, his laboratory explores the central mechanisms responsible for the motor control of pulmonary ventilation and cardiovascular autonomic activity, as well as the neural circuits responsible for cardiorespiratory integration (respiratory-sympathetic coupling). Website: https://zoccal.com (Source: Lattes Curriculum)
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Arterial hypertension (AH) is a cardiovascular disease with a relevant incidence worldwide. Clinical and experimental evidence indicates that increased sympathetic activity to blood vessels primarily contributes to the development of essential AH. Among the factors that can influence the functioning of the sympathetic nervous system is the supply of O2 to the central nervous system (CNS) …
The resting respiratory activity is generated by the synchronized activity of a complex brainstem neural respiratory network, which contains a primary oscillator essential for respiratory rhythmicity. This respiratory oscillator is located within the ventral respiratory column and is composed by pacemaker inspiratory neurons. However, recent studies suggest the presence of a second respir…
Arterial hypertension (AH) is a relevant risk factor for the development of cardiovascular diseases. Clinical and experimental evidence indicates that increased sympathetic activity to blood vessels contributes to the development of essential AH. The reduction in oxygen (O2) availability to the central nervous system (CNS) during the postnatal period may influence the development and func…
Rhythmogenic respiratory neurons on the ventral surface of the medulla, located in the pre-Bötzinger complex (pre-BötC), constitute the primary inspiratory oscillator and are responsible for generating the respiratory rhythm. In situations of reduced O2 (hypoxia) and/or increased CO2 (hypercapnia), the pre-BötC is stimulated to promote an increase in the respiratory frequency. In these si…
(Only some records are available in English at this moment)
Rhythmogenic neurons of the pre-Bötzinger complex (preBötC), located in the ventral medulla, constitute the primary inspiratory oscillator that generates the respiratory rhythm. A second respiratory oscillator was described rostral to the preBötC in the lateral parafacial region (pFL), recruited during conditions of high respiratory drive to generate rhythmic expiratory contractions in th…
The brain functioning depends on adequate supply of oxygen (O2) that must meet its high metabolic demand. In mammals, the partial pressure of O2 (PO2) in the blood is monitored continuously by specialized cells located in the arterial vascular system, in the carotid bodies and the aortic arc. In conditions of hypoxia (reduced PO2), these cells, named peripheral chemoreceptors, drive senso…
| 2 / 2 | Ongoing grants |
| 2 / 2 | Completed research grants |
| 7 / 5 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 13 / 11 | All research grants and scholarships |
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