CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia (IB) (Institutional affiliation for the last research proposal) Birthplace: Brazil
Degree in Chemistry at Federal University of Lavras (2009), master's degree in Organic Chemistry at Federal University of São Carlos (2011) and PhD in Physical Chemistry at State University of Campinas (Unicamp). I have completed a short internship at Erasmus University Medical Center (Rotterdam) in the laboratory of Professor Maikel Peppelenbosch with the collaboration of Dr. Gwenny Fueler. I work as a associate researcher at the Institute of Biology (State University of Campinas) in the OncoBiomarkers Lab. I have experience in Medicinal Chemistry, with an emphasis on Chemoinformatics Methods, Enzyme Kinetics Assays, Protein Crystallography and evaluation of protein activity and expression in cells by Immunoprecipitation and Western Blot. I am currently a professor at the Federal Institute of Education, Science and Technology of São Paulo - Campus São Roque, where I also work with projects in the area of ​​winery waste. (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| Scientists study use of abundant enzyme in tumor cells to monitor cancer treatment |
The great challenge of cancer therapy is to overcome the resistance to chemotherapy and metastasis. Therefore, a better understanding of these processes, the identification of molecular targets, and the development of new drugs with higher efficiency have been aimed of several research groups. In this scenario, our group initiated the investigation on the importance of the low molecular...
Cancer is the common term used to designate a large class of diseases, including malignant tumors in different locations in the body. The increasing number of cases emerges today as a major public health problem. World Health Organization data on cancer incidence, mortality and prevalence worldwide reveals an alarming increasing, with 15 million new cases predicted for 2020 compared to ...
| 2 / 2 | Completed scholarships in Brazil |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 3 |
| Citations | 4 |
| Cit./Article | 1.3 |
| Data from Web of Science | |
FONSECA, EMANUELLA M. B.; TRIVELLA, DANIELA B. B.; SCORSATO, VALERIA; DIAS, MARIANA P.; BAZZO, NATALIA L.; MANDAPATI, KISHORE R.; DE OLIVEIRA, FABIO L.; FERREIRA-HALDER, CARMEN V.; PILLI, RONALDO A.; MIRANDA, PAULO C. M. L.; et al. Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates. Bioorganic & Medicinal Chemistry, v. 23, n. 15, p. 4462-4471, AUG 1 2015. Web of Science Citations: 4. (11/03054-9, 11/15792-4, 09/51602-5, 10/17544-5)
PELIZZARO ROCHA-BRITO, KARIN JULIANE; BARRETO FONSECA, EMANUELLA MARIA; DE FREITAS OLIVEIRA, BRENO GERMANO; DE FATIMA, ANGELO; FERREIRA-HALDER, CARMEN VERISSIMA. Calix[6]arene diminishes receptor tyrosine kinase lifespan in pancreatic cancer cells and inhibits their migration and invasion efficiency. BIOORGANIC CHEMISTRY, v. 100, JUL 2020. Web of Science Citations: 0. (15/11433-0, 13/08896-3)
PEREIRA MACHADO, AGNES THIANE; BARRETO FONSECA, EMANUELLA MARIA; DOS REIS, MARCELO AUGUSTO; SARAIVA, ANTONIO MARCOS; DOS SANTOS, CLELTON APARECIDO; SZYMANSKI DE TOLEDO, MARCELO AUGUSTO; POLIKARPOV, IGOR; DE SOUZA, ANETE PEREIRA; APARICIO, RICARDO; IULEK, JORGE. Conformational variability of the stationary phase survival protein E from Xylella fastidiosa revealed by X-ray crystallography, small-angle X ray scattering studies, and normal mode analysis. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, v. 85, n. 10, p. 1931-1943, OCT 2017. Web of Science Citations: 0. (12/51580-4, 11/15792-4)
(References retrieved automatically from State of São Paulo Research Institutions)
FONSECA, Emanuella Maria Barreto. Novos inibidores de LMW-PTP e CDC25B : planejamento baseado em fragmentos moleculares com uso de métodos in silico, ensaios de inibição e cristalografia de proteínas. Tese (Doutorado) - Instituto de Química. Universidade Estadual de Campinas. (11/15792-4)