Fabíola Freitas de Paula Lopes

• Abstract

  Summer heat stress depression in fertility is a multifactorial problem. It has been shown that elevated temperature compromise follicular dynamics, hormonal secretion, uterine blood flow and endometrial function. Moreover, there is a great amount of evidence indicating that the oocyte and the early embryo are very susceptible to elevated temperature. Such reduction in fertility has been w…

  Immediate and transgenerational epigenetic effects of heat stress on female gametes, AP.PFPMCG.R
• XXXI Annual Meeting of the Brazilian Society of Embryo Technology, AR.BR

• Abstract

  The project envisages acquisition of a microarray platform for the Diadema Campus of Universidade Federal de São Paulo (the Federal University of São Paulo). The microarray technology consists of utilization of a microarrangement in which DNA samples are fixed on spots for hybridization with a pool of mRNAs extracted from biological samples (targets) that were previously marked with fluor…

  Acquisition of a microarray platform for the Diadema Campus of the Federal University of São Paulo, AP.EMU

• Abstract

  In mammals, the growth and maturation of the oocyte require a series of coordinated events that allows fertilization and embryonic development. Exposure of oocytes to adverse environmental conditions compromises cellular and molecular events during oogenesis, reducing oocyte competence. Although the cellular effects caused by heat stress on mammalian gametes have been well studied, little…

  Effect of mouse genotype on DNA methylation and developmental competence of oocytes exposed to in vivo heat stress, BP.IC

• Abstract

  The dairy cattle of tropical and subtropical countries, such as Brazil, are subject to adverse environmental conditions, like heat stress. The negative effect of heat stress on fertility is multifactorial affecting follicular growth, oocyte and pre-implantation embryonic development, among others. Special attention has been given to the oocyte due to the high susceptibility of this cell t…

  Oocyte responses to heat stress, BP.MS
• The role of insulin-like growth factor-I on Bos indicus and Bos taurus oocytes exposed to heat stress, BP.MS

(Only some records are available in English at this moment)