CV Lattes
ResearcherID
Universidade Federal de São Paulo (UNIFESP). Campus Diadema. Instituto de Ciências Ambientais, Químicas e Farmacêuticas (ICAQF) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Biomedicina from University of Santo Amaro - UNISA (1985), phD at Pharmacology from Universidade de São Paulo (2002) and post-doctorate at University of São Paulo (2002-2005) and Federal University of São Paulo (2005-2006). Has experience in Pharmacology, focusing on Cardiorenal Pharmacology and vascular cell signaling induced by peptides from Kallicrein-Kinin and Renin Angiotensin Systems. (Source: Lattes Curriculum)
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The endothelial cell integrates mechanical and biochemical signals capable of stimulating the production of nitric oxide (NO) and superoxide anion (O2*¯). O2*¯ reacts directly with NO, reducing its bioavailability and generating peroxynitrite (ONOO-). In the vasculature the O2*¯ levels are determined mainly by the activity of the enzyme NAD(P) H oxidase and its metabolism in H2O2 by the …
Endothelial cells play a key role throughout the circulation for modulating vascular function by the generation of Endothelium-Derived Relaxing Factors (EDRFs) represented by nitric oxide, prostacyclin and endothelium-derived hyperpolarizing factor, and Endothelium-Derived Constricting Factors (EDCFs), represented by prostaglandin H2 and thromboxane A2, reactive oxygen species, and the pe…
The endothelial cell plays a key role throughout the circulation in view of the generation of Endothelium Derived Relaxing Factors [nitric oxide (NO), prostacyclin and hyperpolarizing factor derived from the endothelium] and Endothelium Derived Contracting Factors [prostaglandin H2 and thromboxane A2, reactive oxygen species, and peptides angiotensin II (Ang II) and endothelin (ET-1)]. In…
| 3 / 2 | Completed research grants |
| 8 / 1 | Completed scholarships in Brazil |
| 11 / 3 | All research grants and scholarships |
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