CV Lattes
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Universidade de São Paulo (USP). Faculdade de Odontologia (FO) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Odontologia from Universidade Federal do Ceará (1993), master's at Clinical Odontology from Universidade Estadual de Campinas (2000) and ph.d. at Clinical Odontology from Universidade Estadual de Campinas (2005). Has experience in Odontology, focusing on Endodontology, acting on the following subjects: endodontia, bactéria, suscetibilidade antimicrobiana, insucesso and cultura. (Source: Lattes Curriculum)
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Although metatranscriptomics (i.e., the collective gene expression analysis) has been successfully applied for the study of caries and periodontal diseases, it has not yet been applied for the functional analysis of the microbiome in endodontic diseases. Acute apical abscess is the most severe form of endodontic diseases. In some cases, dentoalveolar abscess can spread to other areas of t…
The success of endodontic treatment in teeth with necrotic pulp and apical periodontitis depends on the reduction of viable microorganisms of root canals by endodontic disinfection procedures. Our data has indicated an association of molecular methods based on rRNA and rDNA to allow simultaneous evaluation of metabolic activity and abundance of species/ taxa in a bacterial community. This…
The reduction of the viable bacterial load after endodontic disinfection procedures is a key element for treatment success. Since ribosomal RNA(rRNA) indicates microbial viability, molecular approaches based on rRNA are choice methods to assess the antimicrobial effectiveness of endodontic procedures. The objective of the present study is to assess the viability of as-yet-uncultivated bac…
DNA-based molecular methods for detection of microbial species offer advantages over culturing methods. However, one of their disadvantages is the inability to differentiate DNA between viable and dead cells. To overcome this problem, an assay was developed to discriminate between viable or dead bacteria using DNA intercalating substance, propidium monoazide (PMA) dye, in association with…
Post-treatment apical periodontitis is a polymicrobial disease. Identifying the active bacterial composition in endodontic infections is essential to direct effective treatment strategies. Recently, new approaches have been suggested for removal of polymicrobial biofilm-associated infections, including the use of quorum-sensing inhibitors, enzymes, and antimicrobial peptides or amino acid…
| 4 / 3 | Completed research grants |
| 9 / 3 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 14 / 7 | All research grants and scholarships |
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