Beatriz Simonsen Stolf
CV Lattes
ResearcherID
ORCID
Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduate at Ciencias Biologicas from Universidade de São Paulo (1995), master's at Biochemistry from Universidade de São Paulo (1999) and ph.d. at Biochemistry from Universidade de São Paulo (2003). Has experience in Biochemistry, focusing on Biochemistry, acting on the following subjects: marcador molecular, microarray, tireoide, carcinoma and real time rt-pcr. (Source: Lattes Curriculum)
- Role of sCD100 in in vitro and in vivo infection by different Species of Leishmania, AP.R
Abstract
Leishmaniasis is a zoonotic disease caused by protozoa of the genus Leishmania that may be classified in tegumentary (TL) or visceral (VL) forms. In humans and other vertebrate hosts, Leishmania preferentially infects macrophages. Many factors affect the form and severity of the disease, mainly the species of Leishmania and the host immune response. CD100 (Sema 4D) is a glycoprotein of ...
- Role of cTXNPx and OPB in virulence and drug resistance in Leishmania L. amazonensis and search for new virulence factors by comparative proteomics, AP.R
Abstract
Leishmania ssp. are protozoan parasites responsible for a complex of diseases known as leishmaniasis. The parasite has two main forms: promastigote flagellated in the insect digestive tract, and amastigote inside macrophages of the vertebrate host. Survival and multiplication inside these macrophages are guaranteed by evasion mechanisms based on parasite virulence factors. Proteome anal...
- Study of two molecules that potentially modulate the success of macrophage infection by Leishmania amazonensis, AP.R
Abstract
Leishmaniasis affects 12 million people worldwide and two million new cases are reported every year. Leishmania L. amazonensis is an important ethiological agent of the tegumentary form of the disease in Brazil and is responsible for a wide range of clinical forms.In Leishmania life cycle, amastigote forms live and multiplicate inside macrophages from the vertebrate host and promastigot...
- The crucial role of PDI (protein disulfide isomerase) in the phagocytosis of Leishmania chagasi promastigotes, AR.EXT
(Only some records are available in English at this moment)
- Importance of oligopeptidase b (OPB) in the infection of macrophages by l. (l.) amazonensis, BP.MS
Abstract
Leishmania spp. are protozoan parasites that cause leishmaniasis, an endemic disease in more than 98 countries, responsible for more than 1 million new cases every year. The infection can manifest itself in several clinical forms in man, which can be grouped in tegumentary/cutaneous or visceral. The parasite is transmitted to hosts by the bite of female phlebotomine insects. During its ...
- Role of sCD100 in macrophage in vitro infection by Leishmania (Viannia) braziliensis and Leishmania (Leishmania) chagasi and in in vivo infection by Leishmania (Leishmania) amazonensis, BP.PD
Abstract
Leishmaniasis is a zoonotic disease caused by protozoa of the genus Leishmania that may be classified in tegumentary (TL) or visceral (VL) forms. In humans and other vertebrate hosts, Leishmania preferentially infects macrophages. Some factors affect the form and severity of the disease, mainly the species of Leishmania inoculated by the insect vector and the host immune response. CD100...
- Comparative proteomic analysis of promastigote membrane proteins from l. (l.) amazonensis PH8 and LV79 strains, BP.MS
Abstract
Leishmaniasis, a group of diseases caused by the parasite of the genus Leishmania, is endemic in 98 countries and has an estimated annual incidence of more than 1 million cases. The infection can manifest itself in several clinical forms, which are divided into cutaneous, mucocutaneous and visceral. In Brazil, three dermotropic species are predominant, L. (V.) braziliensis, L. (V.) guya...
- Role of the cytoplasmic tryparedoxin peroxidase of Leishmania (Leishmania) amazonensis in resistance to antileishmanial drugs, BP.IC
Abstract
Leishmania (L.) amazonensis is one of the causative species of a complex of diseases known as leishmaniasis. Having a digenetic life cycle, this parasite presents an extracellular stage, known as promastigote, in the gastrointestinal tract of hematophagous sand flies from the genera Phlebotomus and Lutzomyia, and an intracellular stage especially inside macrophages in the mammalian host...
- Analysis of the effect of peptides on the activity of metacaspase and apoptosis in Leishmania (L.) amazonensis, BP.IC
Abstract
Leishmaniasis is an important human disease caused by various species of Leishmania, transmitted by sandflies. In Brazil Leishmania Leishmania amazonensis is one of the important species causing the disease, which can present different clinical forms, most commonly localized cutaneous leishmaniasis (LCL) and more rarely diffuse cutaneous leishmaniasis (LCD).Apoptosis is a type of progra...
(Only some records are available in English at this moment)
- Enzymatic characterization of tryparedoxin cytoplasmic peroxidase of Leishmania (L.) amazonensis and effect of overexpression in resistance to oxidative stress and protein expression of the parasite, BE.EP.MS
Abstract
Leishmania ssp. are protozoan parasites responsible for a complex of diseases known as leishmaniasis. Present two main developmental forms: a flagellated promastigotes in the alimentary tract of the insect vector, and the amastigote no external flagellum, within cells of the mononuclear phagocytic system, preferably macrophages of the vertebrate host. The ability for survival and multip...
| 1 / 1 | Ongoing research grants |
| 5 / 4 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 9 / 7 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 18 / 15 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 7 |
| Citations | 30 |
| Cit./Article | 4.3 |
| Data from Web of Science | |
DE REZENDE, ELOIZA; KAWAHARA, REBECA; PENA, MAURICIO S.; PALMISANO, GIUSEPPE; STOLF, BEATRIZ S.. Quantitative proteomic analysis of amastigotes from Leishmania (L.) amazonensis LV79 and PH8 strains reveals molecular traits associated with the virulence phenotype. PLoS Neglected Tropical Diseases, v. 11, n. 11, NOV 2017. Web of Science Citations: 3. (14/26777-4)
PENA, MAURICIO S.; CABRAL, GUILHERME C.; FOTORAN, WESLEY L.; PEREZ, KATIA R.; STOLF, BEATRIZ S.. Metacaspase-binding peptide inhibits heat shock-induced death in Leishmania (L.) amazonensis. CELL DEATH & DISEASE, v. 8, MAR 2017. Web of Science Citations: 7. (11/12634-9)
TEIXEIRA, PRISCILA CAMILLO; VELASQUEZ, LEONARDO GARCIA; LEPIQUE, ANA PAULA; DE REZENDE, ELOIZA; CAMARGO BONATTO, JOSE MATHEUS; BARCINSKI, MARCELLO ANDRE; CUNHA-NETO, EDECIO; STOLF, BEATRIZ SIMONSEN. Regulation of Leishmania (L.) amazonensis Protein Expression by Host T Cell Dependent Responses: Differential Expression of Oligopeptidase B, Tryparedoxin Peroxidase and HSP70 Isoforms in Amastigotes Isolated from BALB/c and BALB/c Nude Mice. PLoS Neglected Tropical Diseases, v. 9, n. 2, FEB 2015. Web of Science Citations: 11.
CAPELLI-PEIXOTO, JANAINA; MULE, SIMON NGAO; TANO, FABIA TOMIE; PALMISANO, GIUSEPPE; STOLF, BEATRIZ SIMONSEN. Proteomics and Leishmaniasis: Potential Clinical Applications. PROTEOMICS CLINICAL APPLICATIONS, v. 13, n. 6, AUG 2019. Web of Science Citations: 0. (17/26197-6, 17/04287-3, 14/26777-4, 14/06863-3, 18/18257-1, 18/15549-1, 17/04032-5)
VELASQUEZ, LEONARDO G.; GALUPPO, MARIANA K.; DE REZENDE, ELOIZA; BRANDAO, WESLEY N.; PERON, JEAN PIERRE; ULIANA, SILVIA R. B.; DUARTE, MARIA IRMA; STOLF, BEATRIZ S.. Distinct courses of infection with Leishmania (L.) amazonensis are observed in BALB/c, BALB/c nude and C57BL/6 mice. Parasitology, v. 143, n. 6, p. 692-703, MAY 2016. Web of Science Citations: 7.
LUQUE, MARIA C. A.; GALUPPO, MARIANA K.; CAPELLI-PEIXOTO, JANAINA; STOLF, BEATRIZ S.. CD100 Effects in Macrophages and Its Roles in Atherosclerosis. FRONTIERS IN CARDIOVASCULAR MEDICINE, v. 5, SEP 28 2018. Web of Science Citations: 1. (11/12634-9)
GALUPPO, MARIANA K.; DE REZENDE, ELOIZA; FORTI, FABIO L.; CORTEZ, MAURO; CRUZ, MARIO C.; TEIXEIRA, ANDRE A.; GIORDANO, RICARDO J.; STOLF, BEATRIZ S.. CD100/Sema4D Increases Macrophage Infection by Leishmania (Leishmania) amazonensis in a CD72 Dependent Manner. FRONTIERS IN MICROBIOLOGY, v. 9, JUN 5 2018. Web of Science Citations: 1. (11/12634-9)
(References retrieved automatically from State of São Paulo Research Institutions)
GALUPPO, Mariana Kolos. Caracterização funcional de CD100/Sema4D na infecção de macrófagos por Leishmania (Leishmania) amazonensis.. Tese (Doutorado) - Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo. (12/15048-6)
GALUPPO, Mariana Kolos. Análise da atividade de CD100 na modulação da ativação de macrófagos e sua infectividade por Leishmania (Leishmania) amazonensis.. Dissertação (Mestrado) - Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo. (10/02235-7)
PEÑA, Mauricio Scavassini. Estudo dos efeitos da proteína LaLRR17 de Leishmania (L.) amazonensis na infecção do macrófago e identificação de seus possíveis ligantes.. Tese (Doutorado) - Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo. (12/19135-0)
LEITE, Karoline Mathias. Análise da participação da oligopeptidase B e triparedoxina peroxidase citoplasmática na virulência de Leishmania (Leishmania) amazonensis.. Dissertação (Mestrado) - Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo. (13/13527-7)