João Pedreira Duprat Neto

• Abstract

  Sentinel node biopsy is an important tool in melanoma patients staging, since the found of micrometasis leads to lymphatic disease in this population. Nevertheless, other issues such as size, distribution and localization of this metastasis still haven't been incorporated in the management of these cases. Objectives: To evaluate the importance of micrometasis and associated issues as prog…

  Prognostic value of micrometastasis detection in melanoma patients submitted to sentinel node biopsy, AP.R

• Abstract

  Abnormal activation of MAPK, via which normally regulates proliferation, differentiation and cell growth is present in more than 80% of the primary melanomas, mutations and proteins in some way along the RAS-RAF-MEK-ERK. These mutations have been documented in all subtypes of melanoma, including the skin, in which mutations in BRAF and NRAS are more common. It was observed that BRAF was m…

  Comparative analysis of molecular profile mutational status of genes BRAF, NRAS and c-kit in sporadic melanomas, primary and metastatic, AP.R

• Abstract

  Objectives: To evaluate patients undergoing selective lymphadenectomy (sentinel lymph node biopsy) for melanoma, through opto-electronics volumetry and bioimpedance and check the rate of lymphedema in both methods. Patients and methods: 200 patients will be evaluated for axillary or inguinal selective lymphadenectomy for cutaneous melanoma from 1999 to 2010. The patients enrolled will und…

  Evaluation of lymphedema after sentinel lymph node biopsy for melanoma and optoelectronic volumetry by bioimpedance, AP.R

(Only some records are available in English at this moment)

• Abstract

  Abnormal activation of MAPK, via which normally regulates proliferation, differentiation and cell growth is present in more than 80% of the primary melanomas, mutations and proteins in some way along the RAS-RAF-MEK-ERK. These mutations have been documented in all subtypes of melanoma, including the skin, in which mutations in BRAF and NRAS are more common. It was observed that BRAF was m…

  Comparative analysis of molecular profile mutational status of genes BRAF, NRAS and C-Kit in sporadic melanomas, primary and metastatic, BP.DR
• VALIDATION OF OPTO-ELECTRONIC VOLUMETRIC IN BRAZIL, TRANSLATION AND VALIDATION OF QUALITY OF LIFE QUESTIONNAIRE IN PATIENTS WITH LYMPHEDEMA, BP.DR