CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus Baixada Santista. Instituto de Saúde e Sociedade (ISS) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Biological Sciences at the Pontificia Universidade Católica deCampinas (1993), Master of Cellular and Structural Biology from Universidade Estadual de Campinas - UNICAMP (1999) and PhD in Medicine from Unicamp (2004). Currently is associate professor of Department of Biosciences, Universidade Federal de São Paulo - Unifesp. Using experimental models of multiple sclerosis and chronic stress in childhood, we evaluated the growth factors, proinflammatory cytokines expression and stress markers, as well as autoimmune disorders and demyelination. Specifically the action of cytokines and growth factors on the occurrence of cell proliferation, differentiation and apoptosis in cells of the central nervous system, hippocampal plasticity, and the research for immunomodulatory agents on the clinical manifestation of these models. (Source: Lattes Curriculum)
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Multiple sclerosis (MS) is a chronic, demyelinating disease of the central nervous system (CNS). It is probably caused by an autoimmune response in which the inflammatory process destroys the myelin sheath. The main feature of MS is demyelinated lesions that create an environment preventing access of oligodendrocyte precursor cells (OPCs), and their survival and differentiation. Over time…
The multiple sclerosis is a chronic, demyelinating disease of the central nervous system (CNS), which the relapse-remitting course leads to cognitive and motor impairment. The knowledge about the pathogenesis of the multiple sclerosis has been clarified from studies carried with experimental models, as the experimental autoimmune encephalomyelitis (EAE), which depend on genetically suscep…
Numerous studies now provide evidence that psychiatric, metabolic, cardiac, and immunologic disorders have their genesis determined by newborn stress. Newborn stress is mediated by the activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis which promotes changes in limbic system structures, especially in the hippocampus, amygdala and prefrontal cortex. Evidences suggest that children…
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| 1 / 1 | Completed scholarships in Brazil |
| 4 / 4 | All research grants and scholarships |
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