Nilson Antonio de Assunção

• Abstract

  Cri-du-chat syndrome (SCDC) (OMIM # 123450) is a rare genetic disease in which there is a deletion of a part of the short arm of chromosome 5. It is estimated that this syndrome affects from 1 / 15,000 to 1 /50,000 children born in the world. One of the main characteristic is that all births present microcephaly. Another is a large incidence, double the population cardiac problems. The ob…

  Correlation between the Metabolic, Lipidomic and Proteomic Profiles and the 5p Deletion Size of Cri-Du-Chat Syndrome Patients, AP.R

• Abstract

  This project aims to use bioanalytical tools in order to study the radical acetylation of the proteins. The superoxide anion is produced in oxidative stress and reacts with nitric oxide generating peroxynitrite which attacks the alpha carbon of the diacetyl producing radical species. These radicals are able to acetylate proteins and nitrogenous bases in vitro. The exposure to diacetyl is …

  Use of proteomics techniques to study radical acetylation of proteins triggered by products of the reaction biacetyl/peroxinitrite, AP.R

• Correlation between the metabolic, lipidomic and proteomic profiles and the 5p deletion size of Cri-Du-Chat Syndrome patients, BP.TT

• Abstract

  The Cri-Du-Chat Syndrome is a rare disease, characterized by cry like meow cat, mental retardation, microcephaly, ocular hypertelorism, hypotonia, palpebral antimongoloid resulting from deletion in a particular region of chromosome 5. The main of this project is to analyze the amino acid plasma profile of patients with Cri-Du-Chat Syndrome (SCDC), and compare with individuals do not carry…

  Applied study will bioanalytical search profile blood plasma amino acid carriers Syndrome Cri-Du-Chat, BP.MS

• Abstract

  This project will be held the quantification of lead in students and a study of the effects of lead in neurotoxicological academic performance of adolescents between 11 and 15 years of the city of Diadema-SP. At work, the focus will be the neuro-cognitive system, where they will seek to verify the correlation of contents of lead present in students with school performance and aggressivene…

  Evaluation of the Relationship Between the Availability of Lead, Low Academic Performance and Aggression in Students, BP.MS

(Only some records are available in English at this moment)