CV Lattes
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Secretaria da Saúde (São Paulo - Estado). Instituto Butantan (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Instituto de Biociências from Universidade de São Paulo (1982), master's at Fisiologia e Biofísica from Instituto de Ciências Biomédicas-USP (1987) and ph.d. at Fisiologia e Biofísica from Instituto de Ciências Biomédicas-USP (1995). Has experience in Physiology, focusing on Neorofisiology, acting on the following subjects: melatonina, glândula pineal, glandula pineal, melatonin and n-acetiltransferase. (Source: Lattes Curriculum)
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Endogenous phospholipases A2 have a fundamental role in inflammation, neurodegenerative diseases, apoptosis and cellular senescence. Neurotoxins with PLA2 activity (beta-neurotoxins) are found in snake venoms from Elapidae and Viperidae families and these induce neuronal death. Neuronal cultures have been used as a model in order to characterize the mechanisms of action of these neurotoxi…
The aim of this work is to study the role played by melatonin in the control of energy metabolism. Using in vivo and in vitro experiments, in intact or pinealectomized young or old animais, treated or not with melatonin, we are proposing to study the metabolic function and gene expression in the white adipose tissue, skeletal muscular system and the pancreatic B cells and the apoptosis ph…
(Only some records are available in English at this moment)
Toxins with phospholipase A2 (FLA2) activity are found in snake venoms of the Elapidae and Viperidae families and are characterized by their neurotoxic activity, causing neuromuscular junction blockade due to their presynaptic action. Although the action of these toxins occurs at the neuromuscular junction, several studies have used central neuronal cells to characterize their mechanisms …
Melatonin is a hormone synthesized by the pineal gland during the night, thus being a temporal synchronizer of the physiology and behavior of animals. It is a powerful antioxidant with amphiphilic characteristics and can reach all compartments of the organism. Studies have shown that the absence of maternal melatonin during pregnancy and lactation can lead to changes in neural development…
| 8 / 4 | Completed research grants |
| 5 / 2 | Completed scholarships in Brazil |
| 13 / 6 | All research grants and scholarships |
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