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Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia (IB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
José Luiz Proença Módena in research grants and scholarships supported by FAPESP.
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Emerging and reemerging diseases are a public health concern in Brazil and, due to several factors, have a great impact on the Amazon region. This region is characterized by great biodiversity and it is largely populated by a socially vulnerable population. In addition, it has been suffering from recent anthropological activities that promote environmental degradation. In fact, official d…
The arrival of SARS-CoV-2 in Brazil in March 2020 negatively impacted the economy, generated panic in the population and disrupted our country's public and private health systems. It is evident that there is a need for rapid diagnostic / prognostic methods and therapeutic alternatives to deal with this pandemic in our country. Thus, this multidisciplinary project, which involves researche…
(Only some records are available in English at this moment)
Mayaro (MAYV) is an arthritogenic alphavirus, endemic to the Americas and phylogenetically close to the Chikungunya virus. This virus normally circulates in non-human primates, birds and some species of rodents in the wild, mainly in the Amazon region. However, the destruction of forest areas and the redistribution of vectors as a result of global warming have favored the spread of this v…
Despite international appeals regarding the importance of biodiversity and the maintenance of the Amazon ecosystem, our country has faced a weakening of public policies to combat deforestation in the Amazon, with an increase in the deforested area in recent years. In this postdoctoral project, we intend to contribute to the understanding of how deforestation activities (including road con…
(Only some records are available in English at this moment)
Oropouche Orthobunyavirus (OROV) is an arbovirus associated with cases of febrile illness in the Amazon region. A high genetic diversity between orthobunyaviruses generated by genetic rearrangement or mutations makes the development of compounds with directly antiviral activity challenging, thus, host-targeted drugs looks a good alternative to develop antivirals against these pathogens. O…
Emerging viruses can cause great impacts on a susceptible population. A example of this are virus transmitted by arthropods which are widely spread in wild and urban areas, such as Oropouche Vírus (OROV). This is an emergent arbovirus that can be transmitted in urban environmental by the bite of Culicoides paraensis, a hematophagous fly that circulates in the North and Northeast of Brazil…
The Chikungunya virus (CHIKV) is an emerging arbovirus present in tropical and subtropical regions transmitted by the arthropod vector A. aegypti. Although CHIKV infection may be asymptomatic, it usually leads to the development of an acute febrile illness, joint pain and swelling. One of the major complications associated with CHIKV are chronic manifestations such as arthralgia and arthr…
(Only some records are available in English at this moment)
Oropouche orthobunyavirus (OROV) is an emerging arbovirus that causes an exanthematous fever disease associated with neurological complications in some infected patients in the Amazon region from South American countries. Golden hamsters, newborns, and IRF5-/- infected animals are vulnerable and usually die from meningoencephalitis. Thus, since it has been shown that OROV can cross the bl…
The Chikungunya virus (CHIKV) is an emerging arbovirus present in tropical and subtropical regions. One of the major complications associated with CHIKV infection are chronic manifestations such as arthralgia and arthritis. The chronic disease resulting from CHIKV infection has similar characteristics to rheumatoid arthritis (RA) in which dendritic cells (DCs) are implicated in the pathog…
The Oropouche virus (OROV) is an arbovirus with potential to cause epidemics in the most populated regions of Brazil. Individuals infected with OROV develop a febrile illness, which can progress to neurological and hemorrhagic complications. Furthermore, an increased incidence of abortion was reported during major OROV epidemics. However, the pathogenetic mechanisms associated with the he…
| 1 / 1 | Ongoing grants |
| 4 / 4 | Completed research grants |
| 6 / 6 | Ongoing scholarships in Brazil |
| 9 / 7 | Completed scholarships in Brazil |
| 3 / 3 | Completed scholarships abroad |
| 23 / 21 | All research grants and scholarships |
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