CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Biomedicina from Universidade Federal de São Paulo (1981), master's at Biologia Molecular - Fisiologia from Universidade Federal de São Paulo (1985) and doctorate at Biologia Molecular from Universidade Federal de São Paulo (1989). He is currently full professor at Universidade Federal de São Paulo. Has experience in Physiology, focusing on General Physiology, acting on the following subjects: célula mesangial, insuficiencia renal aguda, nefrotoxicidade, diabetes and funcao renal. (Source: Lattes Curriculum)
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Regenerative medicine, defines a new concept related to strategies to restore damaged tissue or accelerate tissue repair after injury. The tissue reconstruction and repair, however, constitute a major challenge of the current biomedical research since the cellular mechanisms underlying tissue reconstruction and repair are still poorly understood and largely unknown. Multipotent stem cells…
Pregnancy is characterized by maternal systemic and intrarenal vasodilation, leading to increases in the renal plasma flow (RPF) and glomerular filtration rate (GFR). These responses are mainly mediated by nitric oxide (NO) and relaxin. The impact of cigarette smoking on the maternal adaptations to pregnancy is unclear. Here we evaluated the effects of chronic exposure to nicotine on syst…
Exposure to nicotine causes several changes in renal function, including reduction of glomerular filtration rate (GFR) and renal plasma flow (RPF) and increased renal vascular resistance. The tubular transport of ions is also affected by the effect of nicotine. The effects of prenatal exposure to nicotine on fetal development are well known, but few studies are directed to the maternal ef…
(Only some records are available in English at this moment)
Clear cell renal cell carcinoma (ccRCC) is frequently associated with inactivation of the Von Hippel-Lindau (VHL) gene, which is essential for regulating hypoxia-inducible factor-1¿ (HIF-1¿). The classic treatment for ccRCC includes tyrosine kinase inhibitors (TKIs), such as sunitinib. However, tumor resistance to these drugs is common and multifactorial, such as activation of alternative…
Air pollution is one of the main environmental problems, significantly affecting public health, mainly causing respiratory diseases. Among the main pollutants is particulate matter (PM), which is considered one of the most harmful substances in atmospheric air. MP can be classified according to its size, with fine MP consisting of particles d 2.5 µm in diameter. Exposure to PM2.5 is assoc…
Acute renal failure (ARF) is a common clinical syndrome. Drug-induced renal injury is one of the most common causes of ARF, especially in Intensive Care Units. Among the various nephrotoxic agents, there may be mentioned bactericidal aminoglycoside antimicrobials, such as gentamicin. The main target of renal injury induced by these antibiotics is the proximal tubular cell, which is highly…
(Only some records are available in English at this moment)
| 15 / 9 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 22 / 11 | Completed scholarships in Brazil |
| 1 / 0 | Completed scholarships abroad |
| 39 / 21 | All research grants and scholarships |
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