Maria Cláudia Nogueira Zerbini

• Abstract

  Aplastic anemia (AA) or bone marrow failure, classified as congenital or acquired, is a bone marrow condition characterized by reduced production of red cells, granulocytes and platelets, resulting in pancytopenia in the peripheral blood. A anemia aplástica adquirida (AAA) is more often observed in children and its differential diagnosis includes congenital bone marrow failures and Myelod…

  Acquired aplastic anemia: bone marrow histology complemented by immunohistochemistry in identifyng unfavorable prognosis, defined by progression to MDS/AML- a comparison between children and adults, AP.R

• Abstract

  Uncontrolled cell proliferation is a key factor in the pathogenesis of neoplasia . In the proliferative process , the neoplastic cells show a preference for anaerobic glycolysis even in the presence of oxygen , a phenomenon known as the " Warburg effect ". The anaerobic metabolism stimulates the conversion of pyruvate to lactic acid, which leads to a reduction of intra cytoplasmic pH. To …

  Monocarboxylate transporters in adrenal cortical tumors: an study of predictive a study of the predictive value of clinical behavior, AP.R
• USCAP 101st ANNUAL MEETING - 2012, AR.EXT

(Only some records are available in English at this moment)

• Abstract

  Primary Adrenal Macronodular Hyperplasia is a rare cause of ACTH-independent Cushing's Disease and has recently been found not to be entirely independent of ACTH secretion. Several groups have studied the molecular mechanisms involved in this disease, with the discovery of the ARMC5 gene mutation being the most recent finding. (AU)

  Primary Macronodular Adrenocortical Hyperplasia: morphological, immunohistochemical study and its correlation with genetic-molecular alterations, BP.DD