CV Lattes
Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia (IB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Faculdade de Agronomia from Universidade Federal do Paraná (1971), master's at Immunology from Universidade Estadual de Campinas (1976) and doctorate at Patologia from The Research Institute For Microbial Disease Of Osaka University (1981). Has experience in Microbiology, focusing on Biology and Fisiology of the Microorganisms, acting on the following subjects: escherichia coli, citotoxina, hemolisina, caracterização and fatores de virulência. (Source: Lattes Curriculum)
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Proteomic analysis combined with molecular studies about virulence properties of pathogenic bacteria has provided numerous resources to understand the mechanisms by which microorganisms develop pathological processes in humans. Preliminary studies showed that all (100%) samples of Escherichia coli associated with human sepsis (SEPEC) adhered and invaded Vero cells (African green monkey ki…
(Only some records are available in English at this moment)
Shiga toxin-producing Escherichia coli (STEC) is a group of enteric pathogens causing diseases in humans such as diarrhea, hemorrhagic colitis and hemolytic uremic syndrome. The virulence factor that defines the STEC strains is the production of potent cytotoxins that inhibit the protein synthesis, called Shiga toxins (Stx). Recently, our research group described the development of peptid…
Escherichia coli isolated from avian cellulits lesions in broiler chickens produce a cytotoxin called Vat (vacuolating autotransporter toxin)that causes intense vacuolization in avian cells, but not in mammalian cells. Previous studies have shown that Vat induced, in broilers, releasing inflammatory cytokines TNF-± and IL-10. Moreover, histological analysis of lesions induced experimental…
Proteomic analysis of pathogenic bacteria, has provided numerous resources to understanding of the mechanisms by which these pathogens develop pathological processes in human. Analysis of the capacity of adhesion of sepsis-associated Escherichia coli (SEPEC) in cells of Hec-1B (endometrial adenocarcinoma human) and Vero (kidney of African green monkey), show that all strains (100%) are ab…
(Only some records are available in English at this moment)
Shiga toxin-producing Escherichia coli (STEC) is a group of enteric pathogens causing diseases in humans such as diarrhea, hemorrhagic colitis and hemolytic uremic syndrome. The virulence factor that defines the STEC strains is the production of potent cytotoxins that inhibit the protein synthesis, called Shiga toxins (Stx). Recently, our research group described the development of peptid…
| 19 / 4 | Completed research grants |
| 33 / 5 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 53 / 10 | All research grants and scholarships |
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